{"id":"W4300692317","doi":"","title":"Effectiveness and safety of tapentadol prolonged release with tapentadol immediate release on-demand for the management of severe, chronic osteoarthritis-related knee pain: results of an open-label, phase 3b study","year":2012,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Pharmacological Effects and Assays","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tapentadol; Osteoarthritis; Medicine; Extended release; Anesthesia; Chronic pain; Pain management; Physical therapy; Opioid; Pharmacology; Alternative medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002698257,0.001142984,0.002122834,0.0003605952,0.0004749179,0.001289201,0.001103569,0.00163488,0.004207965],"category_scores_gemma":[0.001797292,0.0006175552,0.001977383,0.0003818588,0.0008799139,0.001166886,0.0003586607,0.003082782,0.0008429801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008467303,"about_ca_system_score_gemma":0.001211411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001730476,"about_ca_topic_score_gemma":0.003860848,"domain_scores_codex":[0.9987913,0.0006614642,0.00007608227,0.000148639,0.0002020966,0.0001205556],"domain_scores_gemma":[0.9982339,0.00048129,0.000504839,0.0001329194,0.0001421751,0.0005048328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8403981,0.05536034,0.003262421,0.001577091,0.002290742,0.0001248537,0.0003832552,0.000521358,0.0215464,0.00009298117,0.001662852,0.0727796],"study_design_scores_gemma":[0.6555613,0.3241181,0.01634921,0.0001039507,0.0007763123,0.0001427672,0.000103259,0.0005798312,0.001057326,0.00007281919,0.001089494,0.00004559965],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902034,0.005218323,0.0003335959,0.0002625986,0.00009376611,0.001582371,0.001097014,0.00003917844,0.001169784],"genre_scores_gemma":[0.9892124,0.004028009,0.001087593,0.0007645559,0.0002185732,0.001562729,0.001579865,0.00003263333,0.001513656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004207965,"threshold_uncertainty_score":0.01426995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1127855772595679,"score_gpt":0.4623803528350406,"score_spread":0.3495947755754726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}