{"id":"W4300863128","doi":"10.1016/j.bpj.2022.09.043","title":"Effects of ligand binding on dynamics of fatty acid binding protein and interactions with membranes","year":2022,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Ministry of Education - Singapore; National Research Foundation Singapore","keywords":"Chemistry; Ligand (biochemistry); Amide; Fatty acid-binding protein; Hydrogen bond; Membrane; Relaxation (psychology); Biophysics; Binding site; Helix (gastropod); Crystallography; Stereochemistry; Biochemistry; Receptor; Molecule; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003556756,0.0002666718,0.0003649268,0.0001913282,0.0006736972,0.0009932593,0.0005388113,0.0004409069,0.005576627],"category_scores_gemma":[0.001425562,0.000319822,0.0001935329,0.0002805601,0.0006502253,0.0008015721,0.0003326366,0.0009018101,0.0006290552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001158375,"about_ca_system_score_gemma":0.0005071713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004950738,"about_ca_topic_score_gemma":0.003648236,"domain_scores_codex":[0.9997163,0.00007230502,0.00001354719,0.00004871242,0.00005110684,0.00009796434],"domain_scores_gemma":[0.9991952,0.0004931788,0.00006275037,0.00003828843,0.0000667345,0.0001438469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003290489,0.0002397933,0.001031043,0.0001579786,0.00004291224,0.000259109,0.0002437593,0.002018931,0.9869756,0.001552845,0.0005306714,0.003656904],"study_design_scores_gemma":[0.000189559,0.0003507597,0.008395264,0.00002574001,0.00003900814,0.0002163863,0.000447752,0.03497832,0.9520677,0.0006413296,0.002568633,0.0000795021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945629,0.0007671564,0.001335608,0.0004051546,0.00004428565,0.00001167498,0.0002329604,0.00005239048,0.002587881],"genre_scores_gemma":[0.9973767,0.0003498699,0.0006623213,0.0001083771,0.00001263688,0.00001449833,0.000243217,0.00003272286,0.001199747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005576627,"threshold_uncertainty_score":0.01865572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005510774055669691,"score_gpt":0.2273984004653835,"score_spread":0.2218876264097138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}