{"id":"W4301035879","doi":"","title":"Progression-free survival/time to progression as a potential surrogate for overall survival in HR+, HER2– metastatic breast cancer","year":2018,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Metastatic breast cancer; Breast cancer; Oncology; Internal medicine; Medicine; Surrogate endpoint; Cancer; Progression-free survival; Cancer survival; Overall survival","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002244422,0.0006874279,0.001780133,0.001011265,0.0003212346,0.0005810201,0.002292494,0.0001661753,0.01599032],"category_scores_gemma":[0.0005654742,0.000558815,0.0003480696,0.001363307,0.0003651148,0.00193798,0.001224888,0.0005183691,0.0000790651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004636433,"about_ca_system_score_gemma":0.0007505941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00132876,"about_ca_topic_score_gemma":0.0003613903,"domain_scores_codex":[0.9943805,0.0004423261,0.001344508,0.0009921335,0.001773249,0.001067334],"domain_scores_gemma":[0.9955163,0.0003623441,0.001059198,0.001008073,0.001304849,0.0007492466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02930568,0.002363996,0.2255058,0.0008716173,0.001441696,0.0003606339,0.0008511294,0.0003117093,0.2651055,0.00007433038,0.01160842,0.4621995],"study_design_scores_gemma":[0.01626139,0.0005002827,0.8912086,0.009765087,0.0006514285,0.0003275722,0.0002482651,0.00054126,0.04488005,0.01014874,0.02380612,0.001661149],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695752,0.01392202,0.001505668,0.005184241,0.002080099,0.005440016,0.0006949431,0.0001726673,0.001425183],"genre_scores_gemma":[0.9844087,0.001759435,0.007296409,0.001226447,0.00170575,0.001243392,0.00006637993,0.0003569007,0.00193661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6657029,"threshold_uncertainty_score":0.9996864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1375031256721256,"score_gpt":0.5600601352409399,"score_spread":0.4225570095688144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}