{"id":"W4302028211","doi":"10.1016/j.fbr.2022.09.002","title":"Heme sensing and trafficking in fungi","year":2022,"lang":"en","type":"article","venue":"Fungal Biology Reviews","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; National Research Foundation of Korea; Ministry of Science, ICT and Future Planning; National Research Foundation; Canadian Institute for Advanced Research","keywords":"Heme; Vacuole; Biology; Candida albicans; Endomembrane system; Cryptococcus neoformans; Endocytosis; Biochemistry; Fungal protein; Mitochondrion; Intracellular; Cell biology; Yeast; Saccharomyces cerevisiae; Endoplasmic reticulum; Microbiology; Enzyme; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002773899,0.0002469469,0.0003735269,0.0004464539,0.0003235614,0.001299246,0.0002429237,0.00070868,0.001733218],"category_scores_gemma":[0.0002318216,0.00009533388,0.0001410648,0.0004338364,0.0006553931,0.0008869205,0.0005934174,0.000782744,0.0005812675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000603565,"about_ca_system_score_gemma":0.0005327229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009963751,"about_ca_topic_score_gemma":0.001333589,"domain_scores_codex":[0.9998766,0.00002298332,0.00000719327,0.00002119917,0.00003978994,0.00003225042],"domain_scores_gemma":[0.9998953,0.00002938091,0.00001957954,0.000005617594,0.00002285026,0.0000271692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000498357,0.0001216444,0.0009599626,0.003221222,0.00003962088,0.0007671608,0.0005743865,0.000643091,0.2912115,0.03950198,0.02790195,0.6345593],"study_design_scores_gemma":[0.00002620803,0.0003494541,0.01037283,0.001486678,0.00004428627,0.003164727,0.001257489,0.0009935318,0.06945516,0.02908892,0.8837111,0.00004951433],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01568104,0.9677728,0.001970951,0.004399702,0.0008817676,0.000009038229,0.00004664666,0.0000447992,0.009193323],"genre_scores_gemma":[0.124372,0.8563721,0.001832409,0.001151784,0.001151341,0.00001033937,0.00007643106,0.00001444808,0.01501919],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001733218,"threshold_uncertainty_score":0.005798161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04838773495686982,"score_gpt":0.3191909085165911,"score_spread":0.2708031735597213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}