{"id":"W4302761349","doi":"10.1128/spectrum.01290-22","title":"Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective β-Barrel Porin Requirements for Polymer Secretion","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Armand-Frappier Foundation; Department of Science and Technology, Ministry of Science and Technology, India; David and Lucile Packard Foundation","keywords":"Bacterial outer membrane; Periplasmic space; Porin; Secretion; Myxococcus xanthus; Biology; Cell envelope; Inner membrane; Escherichia coli; Biochemistry; Bacteria; Microbiology; Cell biology; Gene; Genetics; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001924323,0.000376266,0.0003845476,0.0001189381,0.0003730806,0.00003270492,0.0004279555,0.0003613741,0.0003488342],"category_scores_gemma":[0.00001934455,0.0003300166,0.0001431357,0.0001504436,0.0002242852,0.000008031541,0.0003701681,0.0002722068,0.000004646188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008874216,"about_ca_system_score_gemma":0.0002541897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008886445,"about_ca_topic_score_gemma":0.000525058,"domain_scores_codex":[0.9978646,0.0001062066,0.0003883294,0.0008666945,0.00008201711,0.0006921574],"domain_scores_gemma":[0.999095,0.000009690802,0.0002783552,0.0004657027,0.00006405191,0.00008724807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002078516,0.00006284792,0.002128906,0.00001281413,0.0002367183,0.000008314445,0.00002822928,0.000004940512,0.9944449,0.0002081312,0.0005450458,0.0002406373],"study_design_scores_gemma":[0.00187918,0.003313821,0.001626536,0.000005124146,0.00005626374,0.0003376277,0.00004964805,0.000008344341,0.973343,0.0001657292,0.01875604,0.0004586792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949318,0.0001819611,0.0007284814,0.001177311,0.001039351,0.001128347,0.0007049738,0.00005196578,0.0000558289],"genre_scores_gemma":[0.9951099,0.00001799701,0.0009942048,0.0004254683,0.0006243279,0.0003365839,0.001935285,0.00005996575,0.0004962987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02110189,"threshold_uncertainty_score":0.9999152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009592476164734237,"score_gpt":0.226333860595274,"score_spread":0.2167413844305398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}