{"id":"W4302761349","doi":"10.1128/spectrum.01290-22","title":"Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective β-Barrel Porin Requirements for Polymer Secretion","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; PROTEO; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Armand-Frappier Foundation; Department of Science and Technology, Ministry of Science and Technology, India; David and Lucile Packard Foundation","keywords":"Bacterial outer membrane; Periplasmic space; Porin; Secretion; Myxococcus xanthus; Biology; Cell envelope; Inner membrane; Escherichia coli; Biochemistry; Bacteria; Microbiology; Cell biology; Gene; Genetics; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008477392,0.0003647077,0.0002064435,0.0001362557,0.0001571856,0.0004076431,0.0001115855,0.0002095298,0.0006332775],"category_scores_gemma":[0.0001671499,0.00009068592,0.0001586639,0.0001328096,0.0002996412,0.0003227767,0.0004275084,0.0002814235,0.0003125622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546822,"about_ca_system_score_gemma":0.0001896283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002035333,"about_ca_topic_score_gemma":0.0001688246,"domain_scores_codex":[0.9999199,0.00001237069,0.000006400624,0.00001678076,0.00002733954,0.00001727514],"domain_scores_gemma":[0.9998746,0.00001481545,0.00005689804,0.000009274532,0.0000121384,0.00003231313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006129746,0.00001282528,0.001648294,0.00002604628,0.000002843292,0.00007443738,0.00001901192,0.00006825579,0.9954764,0.0002926054,0.00002199487,0.002295888],"study_design_scores_gemma":[0.00001621429,0.000374618,0.04211443,0.000007221646,0.00001886515,0.002031837,0.0001694789,0.001182618,0.9504747,0.0003999324,0.00320007,0.00001001059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958218,0.0003829732,0.003050076,0.00006623071,0.000004392912,0.000009214365,0.00008111638,0.00004780689,0.0005363243],"genre_scores_gemma":[0.9954673,0.0003710589,0.002952783,0.00003146964,0.000004656435,0.000008925314,0.0002107625,0.000009477147,0.0009434813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006332775,"threshold_uncertainty_score":0.002118468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009592476164734237,"score_gpt":0.226333860595274,"score_spread":0.2167413844305398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}