{"id":"W4303457093","doi":"10.1200/jco.22.01273","title":"Progression-Free Survival and Patterns of Response in Patients With Relapsed High-Risk Neuroblastoma Treated With Irinotecan/Temozolomide/Dinutuximab/Granulocyte-Macrophage Colony-Stimulating Factor","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Internal medicine; Chemoimmunotherapy; Irinotecan; Temozolomide; Progressive disease; Neuroblastoma; Granulocyte colony-stimulating factor; Oncology; Progression-free survival; Gastroenterology; Surgery; Cancer; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00215177,0.0002621797,0.00171216,0.0003932551,0.0001288439,0.00001109931,0.0002589679,0.0001700262,0.00009424662],"category_scores_gemma":[0.003841141,0.0001649132,0.0001741006,0.0003870255,0.0002821476,0.0001195288,0.0002652204,0.001814397,0.000001248391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000289109,"about_ca_system_score_gemma":0.001041348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001438256,"about_ca_topic_score_gemma":0.0001366308,"domain_scores_codex":[0.9933667,0.002804426,0.00180728,0.0003917494,0.001204302,0.0004255793],"domain_scores_gemma":[0.9914376,0.005175207,0.002070877,0.0003814521,0.0004251209,0.0005097516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2391351,0.004206201,0.7393405,0.00003334723,0.0002658931,0.00407372,0.00005921521,0.0001507207,0.0002001824,0.000001685079,0.00002682831,0.01250656],"study_design_scores_gemma":[0.05918373,0.1802229,0.7595836,0.0001438173,0.0001684448,0.0001359921,0.00005621934,0.00009952807,0.0002065776,0.000009106244,0.00008903829,0.0001010323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981677,0.00003071426,0.00001834733,0.0006467921,0.0001691126,0.000795282,0.0001245469,0.00001503622,0.00003247393],"genre_scores_gemma":[0.9985813,0.00003663295,0.001082786,0.0001084676,0.00005824319,0.00002066578,0.000008934733,0.00004588614,0.00005706708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1799514,"threshold_uncertainty_score":0.7882753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03646536451102339,"score_gpt":0.3768109796344001,"score_spread":0.3403456151233767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}