{"id":"W4303516473","doi":"10.1002/cam4.5271","title":"Achieving tolerance modifies cancer susceptibility profiles in liver transplant recipients","year":2022,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; Canadian Liver Foundation; University Health Network; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; American Society of Transplantation","keywords":"Sirolimus; Calcineurin; Liver transplantation; Medicine; Steatosis; Malignancy; Internal medicine; Cancer; Transplantation; Cancer research; Gastroenterology; Oncology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001689496,0.00009734942,0.0002116873,0.0002815108,0.0001751068,0.0003658379,0.0000714357,0.0001171363,0.0009167804],"category_scores_gemma":[0.00037205,0.00006694149,0.0001754864,0.0003234288,0.0001113093,0.0001356734,0.0001742972,0.0002395697,0.00011198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001153161,"about_ca_system_score_gemma":0.0001116966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002871488,"about_ca_topic_score_gemma":0.0004323509,"domain_scores_codex":[0.9998978,0.00002650837,0.000008120467,0.00002895136,0.00001686964,0.00002165745],"domain_scores_gemma":[0.9997762,0.00003433552,0.0001124444,0.00001494856,0.00001786261,0.00004422825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001236904,0.0001565662,0.9453548,0.00003058487,0.00008547787,0.0002308175,0.0001408293,0.0001622137,0.04185778,0.00006202827,0.00008968193,0.0105923],"study_design_scores_gemma":[0.000004286441,0.0003822678,0.9964247,0.00000333292,0.00004005262,0.0003681689,0.000129365,0.0003055168,0.001996134,0.00007984399,0.0002624333,0.00000389204],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995463,0.0001298061,0.0001090487,0.00001196573,0.000001309735,0.000002379846,0.00006341486,0.00000217955,0.0001336143],"genre_scores_gemma":[0.9995529,0.00006860882,0.0000952144,0.00001491847,0.000002460041,0.000003775119,0.000133123,0.000001416796,0.0001274705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009167804,"threshold_uncertainty_score":0.003066957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02360332488156665,"score_gpt":0.2879230200821982,"score_spread":0.2643196952006316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}