{"id":"W4303516473","doi":"10.1002/cam4.5271","title":"Achieving tolerance modifies cancer susceptibility profiles in liver transplant recipients","year":2022,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; Canadian Liver Foundation; University Health Network; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; American Society of Transplantation","keywords":"Sirolimus; Calcineurin; Liver transplantation; Medicine; Steatosis; Malignancy; Internal medicine; Cancer; Transplantation; Cancer research; Gastroenterology; Oncology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002045661,0.0001665301,0.0002441607,0.00004473993,0.0001072813,0.000003791466,0.0002548785,0.00005571923,0.000533841],"category_scores_gemma":[0.00003175452,0.000152214,0.00004800594,0.0001201783,0.0001781087,0.000004071812,0.0001012229,0.0002118037,9.532816e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001219036,"about_ca_system_score_gemma":0.0001006459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008584902,"about_ca_topic_score_gemma":0.0008114375,"domain_scores_codex":[0.9987215,0.00008587076,0.0002560575,0.0004724135,0.0001829628,0.0002812107],"domain_scores_gemma":[0.9994991,0.00001454896,0.00008749856,0.0002727027,0.00005200989,0.00007410294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003424576,0.00006843636,0.2135671,0.00006921239,0.00003026056,0.000007159866,0.00127985,0.0009918686,0.7767429,0.00001136854,0.002690808,0.004198593],"study_design_scores_gemma":[0.004971268,0.0007710641,0.4188142,0.000527995,0.00009166136,0.00001396555,0.001592223,0.0006272743,0.5195047,0.0001281567,0.05203406,0.0009234195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830781,0.01462793,0.00007737477,0.000757955,0.000562158,0.0002958591,0.0002152385,0.00000928514,0.0003761035],"genre_scores_gemma":[0.9944182,0.003269834,0.00004271413,0.0006343171,0.0005687192,0.0004112601,0.0001497212,0.00001867236,0.0004865614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2572381,"threshold_uncertainty_score":0.6207107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02360332488156665,"score_gpt":0.2879230200821982,"score_spread":0.2643196952006316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}