{"id":"W4303613732","doi":"10.3390/biomedicines10102496","title":"Model of Acute Liver Failure in an Isolated Perfused Porcine Liver—Challenges and Lessons Learned","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; Translational Research in Oncology; University of Alberta","funders":"Edmonton Civic Employees Charitable Assistance Fund; University Hospital Foundation; Canadian Donation and Transplantation Research Program","keywords":"Acetaminophen; Medicine; Liver transplantation; Perfusion; Machine perfusion; Liver disease; Transplantation; Liver injury; Gastroenterology; Internal medicine; Anesthesia; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001955637,0.0008849225,0.0009638021,0.0004698466,0.0003714063,0.001013462,0.001219078,0.001111918,0.001705782],"category_scores_gemma":[0.000686595,0.000278009,0.001048003,0.0002615721,0.0008123883,0.001313202,0.0006249302,0.002754008,0.0008408164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004015134,"about_ca_system_score_gemma":0.0005175541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004492094,"about_ca_topic_score_gemma":0.0006323861,"domain_scores_codex":[0.9992548,0.0002843776,0.00008389487,0.00011404,0.0001543675,0.0001085575],"domain_scores_gemma":[0.9994689,0.0001065352,0.00006856151,0.0001077041,0.0001047383,0.000143681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001646486,0.001284668,0.003210676,0.001396794,0.0001200678,0.002291332,0.0002595931,0.001498992,0.9567747,0.001929433,0.002676671,0.02691057],"study_design_scores_gemma":[0.0009378797,0.08479291,0.04829251,0.00164098,0.001024015,0.03402716,0.002054242,0.03590378,0.664554,0.01056676,0.1156975,0.0005082337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7148494,0.04869019,0.1886483,0.02100057,0.006172196,0.001565117,0.00171832,0.001406194,0.01594978],"genre_scores_gemma":[0.8351749,0.04171642,0.1084631,0.003292545,0.001874582,0.001707348,0.002587596,0.0001802211,0.00500331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001955637,"threshold_uncertainty_score":0.01034254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07547153314804,"score_gpt":0.3221524266196039,"score_spread":0.2466808934715639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}