{"id":"W4303644501","doi":"10.1111/his.14816","title":"Low‐grade oncocytic tumour of the kidney is characterised by genetic alterations of <i>TSC1</i>, <i>TSC2</i>, <i>MTOR</i> or <i>PIK3CA</i> and consistent <scp>GATA3</scp> positivity","year":2022,"lang":"en","type":"article","venue":"Histopathology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"TSC1; Chromophobe cell; Tuberous sclerosis; Oncocytoma; Immunohistochemistry; PTEN; Pathology; Biology; Renal cell carcinoma; TFE3; Cancer research; Eosinophilic; PI3K/AKT/mTOR pathway; TSC2; PAX8; Kidney cancer; Clear cell; Cancer; GATA3; Medicine; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000287492,0.0003243767,0.0008153841,0.0001324787,0.0002878992,0.000009632006,0.0002433853,0.0001032063,0.0001093178],"category_scores_gemma":[0.0001894804,0.0002482549,0.0002495473,0.0003162919,0.0005545105,0.00004957988,0.0003072008,0.0003804522,0.000006644574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003308735,"about_ca_system_score_gemma":0.0005816852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001040034,"about_ca_topic_score_gemma":0.00001156373,"domain_scores_codex":[0.9973273,0.0005138094,0.000723139,0.0005630291,0.0004796828,0.0003930173],"domain_scores_gemma":[0.9980254,0.0002624312,0.0005270656,0.0007904915,0.000126121,0.0002685116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001594499,0.0009256076,0.02010643,0.0002736506,0.0000359396,0.0003235967,0.001805611,0.000005076501,0.9501086,0.00003900403,0.02605653,0.0001605092],"study_design_scores_gemma":[0.006419739,0.003821254,0.2685454,0.0001608231,0.001209223,0.005827202,0.0004388685,0.0001074054,0.6561935,0.00006968873,0.05695324,0.0002536354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927927,0.001822409,0.0000495769,0.001761098,0.0004562585,0.0009591019,0.000957328,0.00003365523,0.00116791],"genre_scores_gemma":[0.9907722,0.0001532337,0.0003469955,0.005570388,0.00005682912,0.0001852998,0.0001267594,0.00004879289,0.002739456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2939151,"threshold_uncertainty_score":0.999997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01401194690251801,"score_gpt":0.2282507106105543,"score_spread":0.2142387637080363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}