{"id":"W4303832659","doi":"10.3390/life12101562","title":"The Role of Systems Biology in Deciphering Asthma Heterogeneity","year":2022,"lang":"en","type":"review","venue":"Life","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Christie (Canada)","funders":"","keywords":"Systems biology; Disease; Asthma; Biology; Computational biology; Mechanism (biology); Profiling (computer programming); Bioinformatics; Confounding; Clinical phenotype; Phenotype; Neuroscience; Medicine; Immunology; Computer science; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001431641,0.001046187,0.001836964,0.002411491,0.0004068955,0.001776345,0.0009853574,0.001694585,0.002260757],"category_scores_gemma":[0.001619545,0.0003037746,0.0008997135,0.002032895,0.001235209,0.002460591,0.001063916,0.003339744,0.001132148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001331535,"about_ca_system_score_gemma":0.002034148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432307,"about_ca_topic_score_gemma":0.001826224,"domain_scores_codex":[0.9995585,0.0001401117,0.00005308158,0.00006539515,0.0001427086,0.00004017552],"domain_scores_gemma":[0.998705,0.0009384009,0.00007327097,0.00003772573,0.0001921463,0.00005340301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005779809,0.00007179821,0.0003944825,0.03304401,0.0002567196,0.0003985253,0.0002799422,0.001496352,0.002899787,0.04521717,0.03089533,0.8849881],"study_design_scores_gemma":[0.0000126057,0.00008628367,0.0007749839,0.006510922,0.000177377,0.001029279,0.0001456685,0.0003825718,0.0008653348,0.02152087,0.9684497,0.0000442889],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007855566,0.9977053,0.0005308648,0.0006160644,0.0002272104,0.000004154255,0.00001153345,0.00001047631,0.0008159092],"genre_scores_gemma":[0.000922064,0.9977805,0.0004969077,0.0003147031,0.0002007853,0.00000809696,0.0000189967,0.000002556274,0.0002554439],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002411491,"threshold_uncertainty_score":0.009661019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04487634719825948,"score_gpt":0.3429197897221524,"score_spread":0.2980434425238929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}