{"id":"W4303832659","doi":"10.3390/life12101562","title":"The Role of Systems Biology in Deciphering Asthma Heterogeneity","year":2022,"lang":"en","type":"review","venue":"Life","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Christie (Canada)","funders":"","keywords":"Systems biology; Disease; Asthma; Biology; Computational biology; Mechanism (biology); Profiling (computer programming); Bioinformatics; Confounding; Clinical phenotype; Phenotype; Neuroscience; Medicine; Immunology; Computer science; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467217,0.0001699156,0.001040568,0.00007382358,0.00006196017,0.000006691802,0.0001831641,0.0001294128,0.00005611928],"category_scores_gemma":[0.0001869752,0.00009736034,0.0003129471,0.0001834102,0.00006420363,0.000008974448,0.0001216337,0.0002468564,0.00001364599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006146133,"about_ca_system_score_gemma":0.0003863845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003628171,"about_ca_topic_score_gemma":0.000008586902,"domain_scores_codex":[0.9986363,0.0003120223,0.0005275892,0.0002031779,0.0001321273,0.0001887524],"domain_scores_gemma":[0.9990196,0.0002435015,0.0002427546,0.0003720798,0.00001409699,0.0001080288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001376843,0.00004871232,0.001279579,0.004759116,0.00009151262,0.00001827848,0.00001125968,0.000003340586,0.00000132309,0.000150445,0.00004589084,0.9935768],"study_design_scores_gemma":[0.0001090279,0.0000887367,0.00009370138,0.001793643,0.00009398878,0.00002155305,0.0001043108,0.000008838463,6.834944e-7,0.000003069789,0.997602,0.00008041183],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008247172,0.9975531,0.000001917717,0.000004073179,0.0002966436,0.0004949847,0.00003462023,0.00001613025,0.0007738429],"genre_scores_gemma":[0.001282255,0.9981729,0.000003734277,0.00002773615,0.0002202307,0.0001780075,0.00003231396,0.0000267345,0.00005612567],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9975561,"threshold_uncertainty_score":0.3970239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04487634719825948,"score_gpt":0.3429197897221524,"score_spread":0.2980434425238929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}