{"id":"W4303958873","doi":"10.3390/molecules27196704","title":"Quercetin and Resveratrol Differentially Decrease Expression of the High-Affinity IgE Receptor (FcεRI) by Human and Mouse Mast Cells","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; National Institute for Nanotechnology","funders":"National Research Council Canada","keywords":"Syk; Resveratrol; Degranulation; MAPK/ERK pathway; Quercetin; Chemistry; Phosphorylation; Mast cell; Signal transduction; Proinflammatory cytokine; Pharmacology; Tyrosine phosphorylation; Molecular biology; Myricetin; Receptor; Cell biology; Biology; Tyrosine kinase; Biochemistry; Immunology; Inflammation; Kaempferol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002617,0.0003000769,0.0001794044,0.0002181788,0.00007633513,0.0001539832,0.0001323032,0.0002739977,0.001217246],"category_scores_gemma":[0.0001130872,0.0001037649,0.0002430852,0.00009696901,0.0001494895,0.0001602455,0.0001091291,0.0003563722,0.0001784419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001827538,"about_ca_system_score_gemma":0.000108778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000590532,"about_ca_topic_score_gemma":0.001161409,"domain_scores_codex":[0.9998488,0.00003949188,0.00001217587,0.00002548037,0.00003496782,0.00003913813],"domain_scores_gemma":[0.9999564,0.000008214373,0.00001198024,0.00000523495,0.000006597199,0.00001157211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004376091,0.00007820969,0.0001248354,0.00002143123,0.000007223118,0.00001679767,0.000008725217,0.00002264457,0.9980438,0.00004052264,0.00002594866,0.001172218],"study_design_scores_gemma":[0.00008000892,0.002411869,0.01168624,0.000005173088,0.00006132256,0.0001883829,0.00002677965,0.0004370864,0.9830068,0.00005018734,0.002040209,0.000006033861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960913,0.001954295,0.0008762952,0.00007242979,0.00002619229,0.0000174981,0.00014184,0.00003013615,0.0007900339],"genre_scores_gemma":[0.9955105,0.0009466565,0.0009159406,0.00007498884,0.00001225653,0.00002610088,0.0003345896,0.000008186793,0.002170814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001217246,"threshold_uncertainty_score":0.00407207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00437884201876708,"score_gpt":0.1796502871647357,"score_spread":0.1752714451459687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}