{"id":"W4303959084","doi":"10.3390/molecules27196589","title":"In Vitro and In Vivo Characterization of 89Zirconium-Labeled Lintuzumab Molecule","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Actinium Pharmaceuticals","keywords":"In vivo; Biodistribution; Ex vivo; In vitro; Flow cytometry; Chemistry; Pharmacology; Monoclonal antibody; Positron emission tomography; Preclinical imaging; Pharmacokinetics; Antibody; Medicine; Nuclear medicine; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475153,0.0002316904,0.0001390521,0.0001759911,0.00008439,0.0001662043,0.0001326137,0.0002115016,0.0009166381],"category_scores_gemma":[0.0001465549,0.00009244149,0.0001394854,0.000124521,0.00009020793,0.00009992308,0.00006120792,0.0002643213,0.0003017149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002502516,"about_ca_system_score_gemma":0.00011679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102106,"about_ca_topic_score_gemma":0.001014075,"domain_scores_codex":[0.9998841,0.00002448952,0.000006243401,0.00002256108,0.00003381956,0.00002879391],"domain_scores_gemma":[0.9999398,0.00001331322,0.00002143894,0.000005257613,0.00001105918,0.000009136766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008113909,0.0000277736,0.0001199372,0.00002550215,0.00000400975,0.00001776819,0.000007308049,0.0001694692,0.9984983,0.00002657495,0.00002608835,0.0009960991],"study_design_scores_gemma":[0.00002173264,0.0007150889,0.002342527,0.000006790452,0.00002238456,0.000149169,0.00001066749,0.0023918,0.9918196,0.00001576722,0.002501586,0.000002826975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895179,0.003679544,0.004547019,0.00007839413,0.00002309721,0.00004495674,0.0002038958,0.00004880887,0.001856301],"genre_scores_gemma":[0.9902812,0.001553615,0.004861134,0.00005904594,0.00001067278,0.00005080475,0.0007041414,0.00001897251,0.002460358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00102106,"threshold_uncertainty_score":0.003066421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01183895272962958,"score_gpt":0.2772793500087427,"score_spread":0.2654403972791131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}