{"id":"W4303986419","doi":"10.1111/bjh.18486","title":"Dasatinib plus <scp>Peg‐Interferon</scp> alpha 2b combination in newly diagnosed chronic phase chronic myeloid leukaemia: Results of a multicenter phase 2 study (<scp>DASA‐PegIFN</scp> study)","year":2022,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada; Merck KGaA","keywords":"Dasatinib; Medicine; Internal medicine; Neutropenia; Gastroenterology; Clinical endpoint; Adverse effect; Pegylated interferon; PEG ratio; Phases of clinical research; Immunology; Imatinib; Myeloid leukemia; Toxicity; Virus; Clinical trial","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002226334,0.0008626793,0.001791961,0.0002329434,0.0002649788,0.0006044271,0.0003488752,0.000559069,0.0008490927],"category_scores_gemma":[0.00084945,0.0003304607,0.0009770138,0.0002750852,0.0004202839,0.0003742558,0.0001860041,0.00138016,0.0002853541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006553877,"about_ca_system_score_gemma":0.0008026623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007032128,"about_ca_topic_score_gemma":0.001519718,"domain_scores_codex":[0.9992641,0.0004109261,0.00004956036,0.00009129151,0.00009701235,0.00008725307],"domain_scores_gemma":[0.9993074,0.0001234847,0.0001848064,0.00004958681,0.00005763526,0.0002771653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5593698,0.05843904,0.05182467,0.001202731,0.004894157,0.0009151834,0.0006360947,0.003455026,0.1415528,0.0002705043,0.004318937,0.1731211],"study_design_scores_gemma":[0.4174385,0.4560241,0.1088333,0.0000561885,0.001285814,0.001649049,0.00009750721,0.002069148,0.008140175,0.0001296866,0.004225498,0.00005103916],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974961,0.001422645,0.0001785861,0.000128147,0.00003516633,0.0002298882,0.0001988523,0.00001418069,0.0002964112],"genre_scores_gemma":[0.9960598,0.001530706,0.0005179947,0.0002119501,0.0001081775,0.000255265,0.0007578934,0.00001166185,0.0005466336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002226334,"threshold_uncertainty_score":0.01177412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02136001394846421,"score_gpt":0.3168797094254256,"score_spread":0.2955196954769614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}