{"id":"W4303987003","doi":"10.1111/imcb.12593","title":"Islet‐specific <scp>CD8</scp><sup>+</sup> T cells gain effector function in the gut lymphoid tissues <i>via</i> bystander activation not molecular mimicry","year":2022,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; University of Queensland; Australian Government; Fondazione Diabete Ricerca; Juvenile Diabetes Research Foundation International; National Institutes of Health; Children's Hospital Foundation; U.S. Department of Health and Human Services","keywords":"Cytotoxic T cell; Biology; T cell; Immunology; Molecular mimicry; Cell biology; Effector; Islet; CD8; Antigen; Immune system; Endocrinology; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001123683,0.0004495785,0.0002347098,0.0001912179,0.00009817979,0.0003144596,0.0001314075,0.0002908996,0.002238314],"category_scores_gemma":[0.0000702611,0.0001073498,0.0001946507,0.00009624952,0.0001837502,0.0002481092,0.0001523508,0.0009654927,0.0005444576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001484946,"about_ca_system_score_gemma":0.00007511809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001361126,"about_ca_topic_score_gemma":0.0001874817,"domain_scores_codex":[0.999866,0.00001833087,0.00001335785,0.00003105378,0.00002781849,0.00004352044],"domain_scores_gemma":[0.9998852,0.0000230832,0.0000250529,0.00001692921,0.00001202654,0.00003766758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009714851,0.00002580058,0.0001828685,0.00001147737,0.000001541932,0.00003738642,0.000005741766,0.00002284512,0.999015,0.00003180058,0.00001903882,0.0005493094],"study_design_scores_gemma":[0.00003391691,0.0006546046,0.004876283,0.000007850167,0.00001398415,0.0004073149,0.00003999606,0.0008660256,0.992069,0.00006661242,0.0009613581,0.000003065059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970452,0.0002183869,0.001064062,0.00004836684,0.00001369278,0.00001567572,0.0001307865,0.00007207147,0.001391705],"genre_scores_gemma":[0.9950389,0.0001611653,0.001769602,0.00007971697,0.00001815622,0.00003418959,0.0002634279,0.00003810488,0.002596756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002238314,"threshold_uncertainty_score":0.007487893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003919718373757959,"score_gpt":0.1894468585843324,"score_spread":0.1855271402105745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}