{"id":"W4304014142","doi":"10.1016/j.chemosphere.2022.136796","title":"Biotransformation of bisphenol-A bis(diphenyl phosphate): In vitro, in silico, and (non-) target analysis for metabolites in rat and bird liver microsomal models","year":2022,"lang":"en","type":"article","venue":"Chemosphere","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; Environment and Climate Change Canada","funders":"","keywords":"Biotransformation; Chemistry; Microsome; Bioaccumulation; Triphenyl phosphate; Toxicokinetics; In silico; Bisphenol A; Glutathione; Biochemistry; Environmental chemistry; Metabolite; Metabolism; In vitro; Chromatography; Enzyme; Organic chemistry; Fire retardant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422449,0.0005828876,0.000219841,0.0003322297,0.0002681825,0.0003042629,0.0002294991,0.0003857794,0.001043736],"category_scores_gemma":[0.0002314588,0.0002741307,0.0004693358,0.0002279466,0.0001841326,0.0002533853,0.0002069538,0.0003600693,0.0004687796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004822217,"about_ca_system_score_gemma":0.0005183035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01094125,"about_ca_topic_score_gemma":0.0121294,"domain_scores_codex":[0.9998426,0.00004441054,0.000007941872,0.00004208311,0.00003319829,0.00002958498],"domain_scores_gemma":[0.9998901,0.0000223416,0.00002058841,0.00001530492,0.00002824318,0.00002334909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005232654,0.00007023506,0.0009050244,0.00006092824,0.00003445047,0.00004943963,0.00003499956,0.001282614,0.9943784,0.00009507626,0.00004137981,0.002524224],"study_design_scores_gemma":[0.000006173819,0.0005632198,0.002452569,0.000001722333,0.00004183732,0.00005978198,0.00001978416,0.002131297,0.9941413,0.00002143618,0.0005554787,0.000005358232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919683,0.0005156567,0.005821628,0.00004211838,0.00001226186,0.00003390027,0.000665608,0.00005572998,0.0008847574],"genre_scores_gemma":[0.9913447,0.0009197938,0.00330657,0.00001790797,0.0000030033,0.0000326467,0.001013699,0.00002507396,0.003336726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01094125,"threshold_uncertainty_score":0.0217551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006753253282124947,"score_gpt":0.2537344563460969,"score_spread":0.2469812030639719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}