{"id":"W4304014786","doi":"10.30683/1929-2279.2022.11.06","title":"Cancer: Evidence Consistent with Epigenetic Carcinogenesis","year":2022,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epigenetics; Carcinogenesis; Cancer; Biology; Mitosis; Mechanism (biology); Lesion; Epigenesis; Cancer research; Genetics; Computational biology; Cell biology; DNA methylation; Gene expression; Medicine; Pathology; Gene; Physics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083802,0.0002901974,0.0004855243,0.001728697,0.0002486593,0.001018361,0.0006070143,0.0009546803,0.00343576],"category_scores_gemma":[0.002190808,0.0001252854,0.0003310746,0.001437085,0.001212957,0.001370865,0.0007674865,0.001348438,0.0009962887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003408657,"about_ca_system_score_gemma":0.0005073586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003796516,"about_ca_topic_score_gemma":0.0005953843,"domain_scores_codex":[0.9996802,0.0000804061,0.00003387857,0.00007698841,0.00009711192,0.00003153219],"domain_scores_gemma":[0.9980756,0.001362183,0.0001799192,0.00008363891,0.0002394407,0.00005926793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00116391,0.0001306625,0.01783966,0.03022784,0.001014749,0.009773672,0.0008004091,0.0005731028,0.02914325,0.09911124,0.03820897,0.7720125],"study_design_scores_gemma":[0.00005710722,0.0005713421,0.0191675,0.004456027,0.0007868169,0.01766144,0.0008292617,0.000171971,0.009152425,0.0396888,0.9073875,0.00006977273],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.006315365,0.9667787,0.0024291,0.009403296,0.00183478,0.00001769583,0.0001709245,0.00005690996,0.01299323],"genre_scores_gemma":[0.03503132,0.9559875,0.001146576,0.002317874,0.003483817,0.00001416111,0.0002058743,0.00001053392,0.001802401],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00343576,"threshold_uncertainty_score":0.01149374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08107009533820288,"score_gpt":0.410267651372523,"score_spread":0.3291975560343201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}