{"id":"W4304014786","doi":"10.30683/1929-2279.2022.11.06","title":"Cancer: Evidence Consistent with Epigenetic Carcinogenesis","year":2022,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epigenetics; Carcinogenesis; Cancer; Biology; Mitosis; Mechanism (biology); Lesion; Epigenesis; Cancer research; Genetics; Computational biology; Cell biology; DNA methylation; Gene expression; Medicine; Pathology; Gene; Physics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001474125,0.0001103586,0.0001834112,0.0001686079,0.0003041636,0.00004427845,0.0004022879,0.00003965376,0.0003175416],"category_scores_gemma":[0.0001246915,0.00008850908,0.00008957995,0.0003160902,0.000141938,0.000008162533,0.0002240219,0.0003135135,0.000001179724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001526618,"about_ca_system_score_gemma":0.001051313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004057951,"about_ca_topic_score_gemma":0.0003573447,"domain_scores_codex":[0.9977633,0.000410502,0.0003168299,0.0002273571,0.0009530018,0.0003290588],"domain_scores_gemma":[0.9984259,0.00007619731,0.0002314902,0.0002536255,0.0008599651,0.0001528181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008301713,0.00007452359,0.1494069,0.00003728175,0.0002060268,0.00003299344,0.0001081163,0.01248079,0.8220806,0.00002185421,0.002085858,0.01263491],"study_design_scores_gemma":[0.0006404159,0.00224694,0.02102436,0.00009123707,0.00006130517,0.00002737383,0.0003596635,0.00004399831,0.8621523,0.00016524,0.1130023,0.0001847779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8629291,0.134904,0.0001157768,0.001619188,0.0001666802,0.0001507338,0.00002785499,0.0000018332,0.00008488167],"genre_scores_gemma":[0.9688449,0.03001329,0.0002409861,0.00009062558,0.0003538831,0.00009450575,0.000005871481,0.00002382356,0.0003321465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1283826,"threshold_uncertainty_score":0.3609296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08107009533820288,"score_gpt":0.410267651372523,"score_spread":0.3291975560343201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}