{"id":"W4304117484","doi":"10.1042/bsr20220094","title":"O-glycosylation and its role in therapeutic proteins","year":2022,"lang":"en","type":"review","venue":"Bioscience Reports","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Glycosylation; Computational biology; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004142537,0.0006082933,0.0007004003,0.001627222,0.0002562401,0.0009574508,0.0004978089,0.0008715828,0.003279677],"category_scores_gemma":[0.0004327234,0.0001947056,0.0003388964,0.001661156,0.0004524256,0.001157208,0.0005376788,0.001653775,0.002303106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005258542,"about_ca_system_score_gemma":0.0006855577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006351137,"about_ca_topic_score_gemma":0.000817088,"domain_scores_codex":[0.999819,0.00002783905,0.00001807404,0.00002611411,0.00008793095,0.00002105464],"domain_scores_gemma":[0.9998937,0.00004492386,0.00001468499,0.000004578891,0.00002864584,0.00001351657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007654077,0.00009153369,0.0001461886,0.0135756,0.00005416384,0.0003796545,0.0001166199,0.0003351097,0.007298444,0.01435901,0.03603232,0.9275348],"study_design_scores_gemma":[0.000005767179,0.00004853074,0.0002245664,0.001057185,0.00002496745,0.0008226357,0.00003023434,0.00003702549,0.0008159681,0.001610256,0.9953154,0.000007345874],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000211203,0.9965999,0.000160517,0.0002725518,0.0002953193,0.000005642886,0.00001629149,0.000009402106,0.002429384],"genre_scores_gemma":[0.001097473,0.9972016,0.0001852909,0.0001986136,0.0001442125,0.00000581661,0.00002365928,0.000001830051,0.001141576],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003279677,"threshold_uncertainty_score":0.01097167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05213125694061933,"score_gpt":0.3494411464445549,"score_spread":0.2973098895039356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}