{"id":"W4304175425","doi":"10.1242/jcs.259272","title":"MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation","year":2022,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Graduiertenakademie, Technische Universität Dresden; Institute of Molecular and Cell Biology; Instytut Biologii Medycznej Polskiej Akademii Nauk; Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Nanyang Technological University; Lee Kong Chian School of Medicine, Nanyang Technological University; Ministry of Education - Singapore; Agency for Science, Technology and Research; Ministry of Education, India; Kanazawa University","keywords":"Biology; Cell biology; Centrosome; Intestinal epithelium; LGR5; Wnt signaling pathway; Casein kinase 1; Organoid; Kinase; Cell cycle; Epithelium; Protein kinase A; Cell; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005270503,0.0001768969,0.0001364097,0.0003922193,0.0002713331,0.0002504923,0.0001237321,0.000187544,0.0007364387],"category_scores_gemma":[0.00008053918,0.0001051396,0.0001109913,0.0001868078,0.0001753271,0.0001593675,0.0001839709,0.0002477955,0.0003151177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005737044,"about_ca_system_score_gemma":0.0002108853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003022675,"about_ca_topic_score_gemma":0.004385263,"domain_scores_codex":[0.9999248,0.00000513688,0.000005632517,0.00001787221,0.00002421595,0.00002244694],"domain_scores_gemma":[0.999915,0.000006337285,0.00002451208,0.000005401916,0.00001649791,0.00003226978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003548967,0.00000241239,0.0005297118,0.00001846737,0.000001390862,0.000151828,0.00001036274,0.00001678326,0.9979987,0.00009704968,0.00005237879,0.001085396],"study_design_scores_gemma":[0.00001029066,0.00008973078,0.07139636,0.00001053763,0.00001234981,0.002039049,0.0000707674,0.0007741041,0.9178358,0.00009461512,0.00765939,0.000006985399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853914,0.006277378,0.004221721,0.0001520677,0.0000317313,0.00001967556,0.0005279412,0.000179236,0.003198745],"genre_scores_gemma":[0.9940993,0.001106432,0.001258762,0.00003215917,0.00000734984,0.00001101144,0.0004419883,0.00001551938,0.00302749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003022675,"threshold_uncertainty_score":0.006010175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006333968375422056,"score_gpt":0.2166928878687834,"score_spread":0.2103589194933614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}