{"id":"W4304175425","doi":"10.1242/jcs.259272","title":"MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation","year":2022,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Graduiertenakademie, Technische Universität Dresden; Institute of Molecular and Cell Biology; Instytut Biologii Medycznej Polskiej Akademii Nauk; Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; Nanyang Technological University; Lee Kong Chian School of Medicine, Nanyang Technological University; Ministry of Education - Singapore; Agency for Science, Technology and Research; Ministry of Education, India; Kanazawa University","keywords":"Biology; Cell biology; Centrosome; Intestinal epithelium; LGR5; Wnt signaling pathway; Casein kinase 1; Organoid; Kinase; Cell cycle; Epithelium; Protein kinase A; Cell; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000280613,0.0001303713,0.0001465822,0.0001159091,0.0003330408,0.00008160512,0.0005573857,0.00003882069,0.00007167341],"category_scores_gemma":[0.00004912629,0.0001164387,0.0001151602,0.0002383854,0.00009715663,0.00001942744,0.0004383948,0.0002173775,0.000004931591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009023493,"about_ca_system_score_gemma":0.0002124909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003863782,"about_ca_topic_score_gemma":0.000002548906,"domain_scores_codex":[0.9985007,0.00004660934,0.0002862481,0.000280921,0.0005326957,0.0003527928],"domain_scores_gemma":[0.9992186,0.000006921766,0.0002752191,0.0001624872,0.0001366921,0.0002001003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001541015,0.0001714877,0.007446832,0.00001919956,0.000004182059,0.00001171931,0.0001682427,0.0002246896,0.9913717,0.00000500413,0.0003485928,0.00007423854],"study_design_scores_gemma":[0.0006236848,0.0006015081,0.01005108,0.00001707645,0.00001259378,0.00009720882,0.0001745769,0.0005777666,0.986259,0.00001390758,0.001427009,0.0001446182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950648,0.0001201763,0.004046244,0.0002492213,0.0001592164,0.0001778398,0.000008414574,0.000003308852,0.0001707622],"genre_scores_gemma":[0.9964661,0.00002246579,0.002526509,0.0002210004,0.0001652304,0.00000744163,0.000003679703,0.00001120541,0.0005763802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005112738,"threshold_uncertainty_score":0.4748233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006333968375422056,"score_gpt":0.2166928878687834,"score_spread":0.2103589194933614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}