{"id":"W4304585003","doi":"10.3390/cancers14204981","title":"HER2-Low Status Does Not Affect Survival Outcomes of Patients with Metastatic Breast Cancer (MBC) Undergoing First-Line Treatment with Endocrine Therapy plus Palbociclib: Results of a Multicenter, Retrospective Cohort Study","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"Medicine; Palbociclib; Metastatic breast cancer; Internal medicine; Breast cancer; Retrospective cohort study; Oncology; Cohort; Cancer; Progression-free survival; Gynecology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007635771,0.0002351591,0.0003416931,0.0004505738,0.000312988,0.0005624627,0.0003108961,0.0002894684,0.001488637],"category_scores_gemma":[0.001642157,0.0002317246,0.0004802066,0.0005999108,0.0002612942,0.0003835552,0.0003235697,0.0003360848,0.0002819142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003179408,"about_ca_system_score_gemma":0.0002940253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00204645,"about_ca_topic_score_gemma":0.001980044,"domain_scores_codex":[0.9996182,0.0001002395,0.00004217217,0.0001181973,0.00006119767,0.00005987646],"domain_scores_gemma":[0.9988379,0.0001920681,0.0005320957,0.0001401884,0.00009642717,0.0002013037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005109397,0.00003870207,0.9981602,0.000004852413,0.00006773136,0.00008063328,0.00003226649,0.00002506254,0.0002217588,0.000006287171,0.00006522966,0.0007863931],"study_design_scores_gemma":[0.00003842756,0.0003001403,0.9985201,0.000003526945,0.00007977455,0.0004825974,0.00009446568,0.00014934,0.00007613775,0.00001172418,0.0002400122,0.000003689012],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994222,0.000157667,0.00003261341,0.00001286197,0.000003137384,0.000004831679,0.0002254923,0.000001090933,0.0001401906],"genre_scores_gemma":[0.999468,0.00006367264,0.00002156913,0.00001314743,0.000007764272,0.000004946656,0.0003634567,0.000001266072,0.00005607929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00204645,"threshold_uncertainty_score":0.004979968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01609266585917917,"score_gpt":0.2964514760097352,"score_spread":0.280358810150556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}