{"id":"W4304689144","doi":"10.1016/j.ajpath.2022.09.004","title":"The Effects of Hyperglycemia on Early Endothelial Activation and the Initiation of Atherosclerosis","year":2022,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Thrombosis and Atherosclerosis Research Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Endothelial dysfunction; Endothelial activation; Medicine; Internal medicine; Endothelium; Cardiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006536577,0.00008024348,0.0003434876,0.00005322436,0.0002147617,0.000003952476,0.0001885425,0.00002849409,0.00001388175],"category_scores_gemma":[0.0002646687,0.00004536482,0.0002210959,0.0001121697,0.001006334,0.00002986492,0.00006157119,0.0002295867,9.773775e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001888704,"about_ca_system_score_gemma":0.00003970525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002682752,"about_ca_topic_score_gemma":4.435024e-7,"domain_scores_codex":[0.9981033,0.001305542,0.0003092036,0.00008454407,0.0000836359,0.0001138418],"domain_scores_gemma":[0.9978798,0.001092196,0.0007697553,0.0001700693,0.00007755546,0.00001061809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002988957,0.0001721281,0.00825068,0.00001139683,0.0005462736,0.00000370278,0.002825963,0.00005372245,0.9111635,0.002915875,0.00009167203,0.07097611],"study_design_scores_gemma":[0.01349536,0.01313964,0.6825861,0.0001099518,0.0006812311,0.0004609894,0.006732512,0.00000307351,0.279376,0.001118018,0.002065514,0.0002316751],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978476,0.001367862,0.0001619905,0.000164452,0.0002754184,0.0001163456,0.00001369444,0.000002703804,0.00004989122],"genre_scores_gemma":[0.999119,0.00064984,0.00001308108,0.0001498591,0.00002580847,0.00001649861,0.000001574099,0.000008863944,0.00001547779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6743354,"threshold_uncertainty_score":0.3707878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004816626673997978,"score_gpt":0.1983943706079755,"score_spread":0.1935777439339775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}