{"id":"W4304692114","doi":"10.1016/s2468-1253(22)00303-x","title":"Etrolizumab as induction and maintenance therapy in patients with moderately to severely active Crohn's disease (BERGAMOT): a randomised, placebo-controlled, double-blind, phase 3 trial","year":2022,"lang":"en","type":"article","venue":"The Lancet. Gastroenterology & hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"F. Hoffmann-La Roche; Roche","keywords":"Medicine; Placebo; Cohort; Internal medicine; Concomitant; Crohn's disease; Adverse effect; Placebo-controlled study; Surgery; Gastroenterology; Disease; Double blind; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005132324,0.0004594348,0.0008586686,0.0002081035,0.0003528598,0.00003774116,0.0004819547,0.0001625432,0.0000708884],"category_scores_gemma":[0.00006187993,0.0003620466,0.0001677135,0.0001373978,0.0003162613,0.00002270681,0.0003163053,0.0005496627,0.000007897257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001284243,"about_ca_system_score_gemma":0.0002647592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005736735,"about_ca_topic_score_gemma":0.0005045554,"domain_scores_codex":[0.996078,0.001215409,0.0005543165,0.0009384821,0.0002772,0.0009366288],"domain_scores_gemma":[0.9984814,0.00004792147,0.0003465159,0.000686131,0.000148561,0.0002894502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9521092,0.0008742318,0.04412953,0.000008238142,0.0003520552,0.0003481831,0.0001572895,0.0006820117,0.0001274834,0.00003410077,0.0006529634,0.0005246818],"study_design_scores_gemma":[0.8530747,0.005436735,0.1396499,0.000005698649,0.00009404642,0.00007042882,0.00008231147,0.0003035498,0.00004291804,0.00008962653,0.0008953004,0.0002548715],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925205,0.00006556122,0.0002491656,0.001303492,0.0004534145,0.005149007,0.0001428313,0.00003011949,0.00008597197],"genre_scores_gemma":[0.9905219,0.00003968349,0.00003477102,0.004465893,0.0002942817,0.004274921,0.0002199376,0.00005799215,0.00009058585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09903459,"threshold_uncertainty_score":0.9998832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422734792694747,"score_gpt":0.2597048531549768,"score_spread":0.2454775052280293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}