{"id":"W4304776316","doi":"10.26434/chemrxiv-2022-ldq4b","title":"Stretching Peptides","year":2022,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Science Foundation","keywords":"Polyproline helix; Tripeptide; Chemistry; Peptide; Helix (gastropod); Peptidomimetic; Combinatorial chemistry; Small molecule; Stereochemistry; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001294749,0.0004303946,0.0001722122,0.0001558361,0.0001683592,0.0002466941,0.0003304585,0.0003580256,0.01218638],"category_scores_gemma":[0.0002075118,0.0001393342,0.0001860254,0.0001993996,0.0002036299,0.0004873788,0.0003354603,0.0006281144,0.003519349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001809534,"about_ca_system_score_gemma":0.0001227086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001270044,"about_ca_topic_score_gemma":0.0001638509,"domain_scores_codex":[0.9998912,0.000007731316,0.000007020958,0.0000443287,0.00002758212,0.00002223874],"domain_scores_gemma":[0.999895,0.00002388924,0.00003274652,0.00001432375,0.00001420818,0.00001981383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002031368,0.00003806272,0.0001058786,0.0002544468,0.00001131889,0.0001376136,0.00004099891,0.0009033802,0.9732254,0.002141539,0.000788315,0.02214982],"study_design_scores_gemma":[0.0000935105,0.001215383,0.001332054,0.00003803519,0.00002036934,0.0005487313,0.00003790425,0.001365238,0.9206578,0.001042641,0.07361253,0.0000356507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8849204,0.01124112,0.04902405,0.0006930689,0.0009744205,0.0003709329,0.002744371,0.0007242293,0.04930744],"genre_scores_gemma":[0.9116811,0.006213665,0.03407152,0.001158195,0.0001756562,0.0003870919,0.002414028,0.0001880173,0.04371074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01218638,"threshold_uncertainty_score":0.04076749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03115006485696067,"score_gpt":0.306212582683224,"score_spread":0.2750625178262633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}