{"id":"W4304783156","doi":"10.54097/hset.v14i.1840","title":"Immune Checkpoint inhibitor Therapy in Various Cancers","year":2022,"lang":"en","type":"article","venue":"Highlights in Science Engineering and Technology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Immune system; Immunotherapy; Immune checkpoint; CTLA-4; Cancer immunotherapy; Tumor microenvironment; Ipilimumab; Monoclonal antibody; Cancer; Immunology; Medicine; Cancer research; T cell; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002129602,0.0003172788,0.0004251622,0.0006569514,0.0001906544,0.0003500132,0.0002519428,0.0003826988,0.002223474],"category_scores_gemma":[0.0001958343,0.00007136353,0.0003470648,0.0006071933,0.0001574231,0.0003329301,0.0003129334,0.0008391208,0.0005820764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003293483,"about_ca_system_score_gemma":0.0004103145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004080044,"about_ca_topic_score_gemma":0.001048655,"domain_scores_codex":[0.9999083,0.00001873418,0.00001062812,0.00001632271,0.00003011927,0.00001588478],"domain_scores_gemma":[0.9999619,0.000009985517,0.00001003027,0.00000225619,0.000009741847,0.00000616023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002541931,0.0001838962,0.0009022523,0.004881539,0.0001078773,0.0006962232,0.00007085457,0.0006137952,0.01350783,0.006257135,0.02245825,0.9500661],"study_design_scores_gemma":[0.0001635578,0.0008444792,0.005074314,0.001323005,0.0002541663,0.005310247,0.00007684676,0.0005882728,0.01060801,0.004212255,0.9715176,0.00002733624],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003872409,0.9880854,0.0008678784,0.0008183374,0.0004019182,0.00002427108,0.00005698684,0.00003126122,0.005841524],"genre_scores_gemma":[0.04410134,0.9463931,0.001392489,0.00136799,0.0005864466,0.00005679855,0.0002421041,0.00000812068,0.005851642],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002223474,"threshold_uncertainty_score":0.007438242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007117906881766555,"score_gpt":0.2298261016890909,"score_spread":0.2227081948073243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}