{"id":"W4304783156","doi":"10.54097/hset.v14i.1840","title":"Immune Checkpoint inhibitor Therapy in Various Cancers","year":2022,"lang":"en","type":"article","venue":"Highlights in Science Engineering and Technology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Immune system; Immunotherapy; Immune checkpoint; CTLA-4; Cancer immunotherapy; Tumor microenvironment; Ipilimumab; Monoclonal antibody; Cancer; Immunology; Medicine; Cancer research; T cell; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004605129,0.0001073493,0.000199602,0.001164845,0.0001079349,0.00001124306,0.0001847941,0.00006011966,0.00002404124],"category_scores_gemma":[0.00002683954,0.00009392903,0.00002181168,0.002434072,0.0002853886,0.00005986698,0.000100648,0.0003100002,0.000002001109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005385142,"about_ca_system_score_gemma":0.000206008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003390969,"about_ca_topic_score_gemma":0.00003070162,"domain_scores_codex":[0.9989468,0.000006801134,0.0002268758,0.0003006072,0.0001974026,0.0003215307],"domain_scores_gemma":[0.9996752,0.00001504069,0.00003378273,0.0002231914,0.00001834121,0.00003444882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002469882,0.00010588,0.00389852,0.00001779922,0.0000144156,0.000154798,0.000828634,0.0007091098,0.9695581,0.006883687,0.0000267139,0.01755537],"study_design_scores_gemma":[0.01339618,0.003151143,0.1002088,0.0003372032,0.00001273279,0.001010747,0.001660986,0.01368376,0.6525176,0.0009278285,0.2120885,0.00100457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923461,0.003184554,0.00001821401,0.003546928,0.0004298422,0.0002046465,0.000001792838,0.000113645,0.0001542496],"genre_scores_gemma":[0.9983336,0.0009372198,0.0004835684,0.00005386697,0.00002061394,0.0001019022,8.00614e-7,0.000009968397,0.00005847333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3170405,"threshold_uncertainty_score":0.3830315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007117906881766555,"score_gpt":0.2298261016890909,"score_spread":0.2227081948073243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}