{"id":"W4304808123","doi":"10.1038/s41541-022-00540-7","title":"Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada; Government of Canada","keywords":"Immunogenicity; Antigen; Virology; Neutralizing antibody; Immune system; Spike Protein; Antibody; Immunology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Biology; Disease; Medicine; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001769618,0.0003213936,0.0001248056,0.0001224629,0.00006646816,0.0002148421,0.0001123275,0.0002219962,0.000611289],"category_scores_gemma":[0.0001954401,0.00009053471,0.0001277953,0.00009557354,0.0001401308,0.0001932397,0.0001981156,0.0004084592,0.0001346148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001709251,"about_ca_system_score_gemma":0.0001173791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002934638,"about_ca_topic_score_gemma":0.0003382495,"domain_scores_codex":[0.9998786,0.00002000604,0.000008858394,0.00002182706,0.00003768397,0.00003296935],"domain_scores_gemma":[0.9999254,0.00001159331,0.000021933,0.000008132099,0.00001547153,0.00001744879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005954928,0.00004078443,0.0002899704,0.0000104119,0.000003124104,0.00002434802,0.00001210448,0.0001214274,0.9985383,0.00003604716,0.00001909378,0.0008449067],"study_design_scores_gemma":[0.00003283446,0.003493621,0.009211674,0.000007113395,0.00002219522,0.0004229417,0.00004185357,0.001658127,0.9833601,0.00006143266,0.001680884,0.000007232129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998789,0.00008327862,0.0007217952,0.00001622165,0.000007211587,0.00001101358,0.00003218822,0.00000664992,0.0003324965],"genre_scores_gemma":[0.9987879,0.00006443697,0.000578395,0.00002923295,0.000004595207,0.000006807254,0.0001831028,0.00000408861,0.0003413325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000611289,"threshold_uncertainty_score":0.002044916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08750393595213496,"score_gpt":0.3627206318302117,"score_spread":0.2752166958780768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}