{"id":"W4304808123","doi":"10.1038/s41541-022-00540-7","title":"Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada; Government of Canada","keywords":"Immunogenicity; Antigen; Virology; Neutralizing antibody; Immune system; Spike Protein; Antibody; Immunology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Biology; Disease; Medicine; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003751763,0.0002304219,0.0007259238,0.0002090746,0.0001377898,0.00001195844,0.0004926967,0.000102776,0.0003286908],"category_scores_gemma":[0.0002179581,0.0002143375,0.000251412,0.0005482859,0.00008138845,0.0000799405,0.0004665083,0.0003439815,0.00003574194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008432586,"about_ca_system_score_gemma":0.0003942655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006234789,"about_ca_topic_score_gemma":0.0003546067,"domain_scores_codex":[0.9977417,0.0001506,0.0006184809,0.0004300661,0.0006672599,0.0003919227],"domain_scores_gemma":[0.9983074,0.000205767,0.0002572805,0.0008647525,0.0003322361,0.00003253108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008537894,0.0002865864,0.1960333,0.00007656631,0.0002780586,0.0000317349,0.0004643163,0.000001590189,0.799321,0.00002686128,0.001187405,0.001438757],"study_design_scores_gemma":[0.003079892,0.0003758875,0.151328,0.00004698419,0.0001498881,0.00002804966,0.0002134723,0.0001314515,0.8248534,0.0002110281,0.01940324,0.0001786279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956197,0.002097028,0.0001825779,0.00025161,0.0002692203,0.0004498098,0.0003178753,0.00005390094,0.0007582536],"genre_scores_gemma":[0.9947981,0.00002871858,0.0004924085,0.004352316,0.0001409084,0.00003069746,0.00006222534,0.00004349162,0.00005111145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04470529,"threshold_uncertainty_score":0.9425178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08750393595213496,"score_gpt":0.3627206318302117,"score_spread":0.2752166958780768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}