{"id":"W4304890405","doi":"10.1111/dth.15931","title":"Tapinarof for the treatment of psoriasis","year":2022,"lang":"en","type":"review","venue":"Dermatologic Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Dermatrials Research","funders":"","keywords":"Medicine; Psoriasis; Adverse effect; Dermatology; Folliculitis; Clinical trial; Tachyphylaxis; Upper respiratory tract infection; Clinical endpoint; Safety profile; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000399439,0.0008578181,0.0005903696,0.001117038,0.0004838463,0.0007982566,0.0004798744,0.00117284,0.05222632],"category_scores_gemma":[0.0004586022,0.0001193713,0.0008593086,0.0006639387,0.0003043358,0.0005463434,0.0006219762,0.002746021,0.02154036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003403579,"about_ca_system_score_gemma":0.0004493446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003337093,"about_ca_topic_score_gemma":0.00083562,"domain_scores_codex":[0.999681,0.00004877006,0.000018846,0.00006393858,0.0001441069,0.00004343063],"domain_scores_gemma":[0.9997625,0.00004079843,0.00005510045,0.00001511899,0.00005427123,0.00007228243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001016092,0.0005540414,0.0002688927,0.002814284,0.00008953713,0.0006646678,0.00007025417,0.0001748047,0.02161967,0.003723612,0.1268371,0.8421671],"study_design_scores_gemma":[0.001329759,0.001654105,0.002565783,0.001150863,0.0001180093,0.005176475,0.0000390603,0.0002474818,0.004470673,0.003463536,0.9797413,0.00004297654],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01560744,0.7416667,0.00820324,0.01746341,0.00697721,0.000656979,0.002013332,0.002033713,0.2053779],"genre_scores_gemma":[0.1540657,0.5598756,0.01068025,0.02538954,0.00923792,0.0005998372,0.004727575,0.0004349297,0.2349887],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.05222632,"threshold_uncertainty_score":0.1747144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139112360014542,"score_gpt":0.3328378417601215,"score_spread":0.2189266057586673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}