{"id":"W4306249959","doi":"10.1182/bloodadvances.2022007360","title":"Transformation of FL into DLBCL with a PMBL gene expression signature","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"National Cancer Institute","keywords":"BCL6; Biology; Germinal center; Cancer research; Lymphoma; Follicular lymphoma; Diffuse large B-cell lymphoma; Genetics; B cell; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004136588,0.00008302031,0.0001617647,0.00004684921,0.00009289575,0.000003150924,0.00004252287,0.00001899612,0.00008820221],"category_scores_gemma":[0.00000429088,0.00005441807,0.00004300518,0.0001244108,0.00002058991,0.0001117055,0.00001483426,0.00005591154,0.000001409793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003011947,"about_ca_system_score_gemma":0.00004362735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001602193,"about_ca_topic_score_gemma":0.000006513478,"domain_scores_codex":[0.9993681,0.00001963234,0.0001303681,0.000125131,0.0002674164,0.00008935215],"domain_scores_gemma":[0.9997149,0.00002297846,0.000069562,0.0001205756,0.00003015493,0.00004187295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003492346,0.01465684,0.1973221,0.001214827,0.0007206096,0.0005104282,0.01604118,0.002194896,0.5780185,0.001727843,0.0008941754,0.1832062],"study_design_scores_gemma":[0.007363934,0.00185818,0.01208583,0.0001282397,0.0002404822,0.00009639532,0.0009577785,0.00002073307,0.9546733,0.000153313,0.02231533,0.0001064251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875612,0.009457608,0.0001089958,0.0004667004,0.00005429564,0.0003493153,0.0000217954,0.00003227389,0.001947854],"genre_scores_gemma":[0.9950224,0.0002774264,0.004255902,0.0001169866,0.00002969119,0.0001494698,0.00006404805,0.000008084288,0.00007596729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3766548,"threshold_uncertainty_score":0.2219104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005289266285482754,"score_gpt":0.2360521989720586,"score_spread":0.2307629326865759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}