{"id":"W4306319652","doi":"10.1093/eurheartj/ehac544.2872","title":"Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells","year":2022,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Induced pluripotent stem cell; Medicine; Cell biology; Myocyte; Wnt signaling pathway; Sarcomere; Internal medicine; Endocrinology; Biology; Signal transduction; Embryonic stem cell; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002887385,0.000341679,0.0002878285,0.000224615,0.0001121066,0.0002810613,0.0002311443,0.0003120426,0.002776407],"category_scores_gemma":[0.000129468,0.0001291421,0.0002604801,0.0001670626,0.0001326414,0.0002169766,0.0002971771,0.0004364137,0.000664309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000732313,"about_ca_system_score_gemma":0.0001527185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000793874,"about_ca_topic_score_gemma":0.0001144413,"domain_scores_codex":[0.9998642,0.00001187046,0.00002912263,0.00002937182,0.00004983438,0.00001555493],"domain_scores_gemma":[0.9999044,0.00001291506,0.00002452685,0.00001280891,0.00002101786,0.00002431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008262034,0.00003729311,0.0003622445,0.0001408031,0.00001087875,0.0001121935,0.00002420281,0.0001380609,0.9915757,0.0003402391,0.0001975075,0.006978276],"study_design_scores_gemma":[0.0001277664,0.000919443,0.003757077,0.00004740347,0.00004880803,0.0007067253,0.0000437767,0.002196175,0.9816713,0.0003249483,0.01014585,0.00001066206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8916339,0.004335815,0.09094565,0.0002955899,0.0003586885,0.0005566279,0.003862805,0.0005236341,0.007487269],"genre_scores_gemma":[0.9459903,0.002140986,0.04004112,0.000220867,0.00009003505,0.0004467393,0.004298867,0.00006127,0.006709732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002776407,"threshold_uncertainty_score":0.009288013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05121909233160553,"score_gpt":0.2847271656221164,"score_spread":0.2335080732905108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}