{"id":"W4306353179","doi":"10.1093/nar/gkac890","title":"KRCC1, a modulator of the DNA damage response","year":2022,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; U.S. Department of Defense","keywords":"Biology; DNA damage; CHEK1; G2-M DNA damage checkpoint; RAD51; DNA repair; Homologous recombination; Recombinase; Cell biology; Cell cycle; Cell cycle checkpoint; Checkpoint Kinase 2; DNA; Cancer research; Genetics; Cancer; Gene; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008000922,0.00033644,0.0001774006,0.0002234181,0.0002876968,0.0003347825,0.0001408541,0.0002730932,0.0009650858],"category_scores_gemma":[0.000123402,0.0001103221,0.00009231103,0.0001427933,0.0001490666,0.000184781,0.0001506763,0.0002621776,0.0004645355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005032675,"about_ca_system_score_gemma":0.0001902676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004984993,"about_ca_topic_score_gemma":0.0007282825,"domain_scores_codex":[0.9999328,0.000008047686,0.000003145994,0.00002392494,0.0000160569,0.00001606024],"domain_scores_gemma":[0.9999118,0.000008427221,0.00003585825,0.000005544397,0.00001210068,0.00002625731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006311564,0.000007667669,0.0007379588,0.00004469947,0.000002852899,0.0001091096,0.00001143521,0.0001180521,0.9960632,0.0002014389,0.0001737771,0.002466646],"study_design_scores_gemma":[0.00001431615,0.0001497154,0.02195082,0.00001515998,0.00001415769,0.00142136,0.00004252797,0.001427309,0.962411,0.0002537247,0.01228813,0.00001181718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9615643,0.02623715,0.005916434,0.0006641427,0.000118832,0.0000671125,0.0007470309,0.0003124799,0.004372459],"genre_scores_gemma":[0.9918675,0.003625366,0.00130079,0.00007111768,0.00002359831,0.00001459821,0.000467388,0.00001101628,0.002618645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009650858,"threshold_uncertainty_score":0.0036515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02778298046591978,"score_gpt":0.3165865983819934,"score_spread":0.2888036179160736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}