{"id":"W4306353734","doi":"10.1101/2022.10.14.512294","title":"Long-read genome sequencing accelerated the cloning of <i>Pm69</i> by resolving the complexity of a rapidly evolving resistance gene cluster in wheat","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Wheat and Barley Genetics and Pathology","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Saskatchewan","funders":"Planning and Budgeting Committee of the Council for Higher Education of Israel; European Regional Development Fund; Council for Higher Education; Israel Science Foundation; Genome Canada","keywords":"Genetics; Biology; Contig; Genome; Gene; Positional cloning; Cloning (programming); Chromosome; Polyploid; Gene cluster; Powdery mildew; Computational biology; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000292516,0.0004065979,0.0002379919,0.0001822298,0.0001986865,0.0004470895,0.0001862947,0.0003032211,0.002239938],"category_scores_gemma":[0.000382778,0.0001613475,0.0003549544,0.0001876757,0.0001391278,0.0002778147,0.0003189444,0.0007731616,0.001518108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001676519,"about_ca_system_score_gemma":0.0002052907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006059114,"about_ca_topic_score_gemma":0.0009796064,"domain_scores_codex":[0.9998456,0.00002158187,0.00001222203,0.00005291323,0.00004317195,0.00002441428],"domain_scores_gemma":[0.9998301,0.00003656053,0.00003580657,0.00003390964,0.00002935581,0.00003434694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000498244,0.00001227996,0.0002687716,0.00002688189,0.000004195153,0.00005276869,0.00001788024,0.0001157169,0.995932,0.0001495767,0.0001325462,0.003237468],"study_design_scores_gemma":[0.0000292358,0.000215578,0.01295896,0.00001270835,0.00002848943,0.0004241917,0.0000476061,0.005789755,0.9670003,0.0004800235,0.01299888,0.00001420613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8586408,0.0003946849,0.1303927,0.0003352618,0.0001386174,0.0001436756,0.004073874,0.002192399,0.003688073],"genre_scores_gemma":[0.8530638,0.0004332403,0.1232839,0.0001935244,0.00006111491,0.00009464056,0.0141641,0.0009557956,0.00774983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002239938,"threshold_uncertainty_score":0.007493377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03647149862078441,"score_gpt":0.2218866597394618,"score_spread":0.1854151611186774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}