{"id":"W4306360085","doi":"10.1172/jci164219","title":"The curious case of tryptophan in pregnancy","year":2022,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Preeclampsia; Pregnancy; Kynurenine; Medicine; Fetus; Kidney; Kynurenine pathway; Ischemia; Tryptophan; Physiology; Immunology; Endocrinology; Bioinformatics; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001808152,0.0006946215,0.001080875,0.0005900807,0.002570469,0.001946175,0.001201174,0.01960361,0.001017029],"category_scores_gemma":[0.01532095,0.0004602201,0.0006640095,0.0004585054,0.003045768,0.003136077,0.001086257,0.0177947,0.0007017275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002404458,"about_ca_system_score_gemma":0.002014743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002102826,"about_ca_topic_score_gemma":0.003626138,"domain_scores_codex":[0.9980363,0.001001389,0.0002090124,0.0002566232,0.0003121162,0.0001846089],"domain_scores_gemma":[0.9956771,0.00310074,0.0002584028,0.0002003791,0.0002520001,0.0005114108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002737719,0.0001096368,0.004541181,0.0004715257,0.00008543338,0.1637583,0.001714223,0.0001709976,0.001034624,0.02423501,0.750891,0.05271428],"study_design_scores_gemma":[0.000198211,0.0002295056,0.003951312,0.001497814,0.00009523194,0.2614768,0.002391886,0.0007088591,0.0008271902,0.03293866,0.6955727,0.0001118369],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003137042,0.02382217,0.0002403424,0.9546868,0.01400083,0.00001659902,0.0000197292,0.00003387162,0.004042589],"genre_scores_gemma":[0.04775057,0.02165717,0.0006331808,0.8445915,0.08214059,0.00005226741,0.00001795747,0.00002624899,0.003130444],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01960361,"threshold_uncertainty_score":0.01744562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1089360297782825,"score_gpt":0.3951994232567567,"score_spread":0.2862633934784742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}