{"id":"W4306366816","doi":"10.3390/cancers14205048","title":"Quantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Phospholipid Research Center; Mach-Gaensslen Foundation of Canada","keywords":"Nucleolin; Peptide; Internalization; Cancer research; Chemistry; Immunotoxin; Targeted drug delivery; Cell culture; Molecular biology; Cell; Drug delivery; Cell biology; Cytotoxicity; Biochemistry; Biology; Cytoplasm; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339609,0.0002109211,0.0001887796,0.000184343,0.0001070422,0.0001205101,0.0001214877,0.000340398,0.0005698202],"category_scores_gemma":[0.0001274299,0.00009128214,0.0001294035,0.00009555924,0.0001144534,0.00008835539,0.0001001593,0.0001215237,0.0002441476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185719,"about_ca_system_score_gemma":0.00009644411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007806267,"about_ca_topic_score_gemma":0.001197028,"domain_scores_codex":[0.9998871,0.00002425798,0.000005999064,0.00002606779,0.00003444892,0.00002216668],"domain_scores_gemma":[0.9999452,0.0000194991,0.00001018486,0.000004320909,0.00001230586,0.000008608952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002080017,0.00000615577,0.000113125,0.000007558538,9.498616e-7,0.00001262469,0.000003267914,0.00003976194,0.9994838,0.000007853626,0.00000644881,0.0002974891],"study_design_scores_gemma":[0.000004925158,0.0001313493,0.002859636,0.000001334304,0.000005736963,0.000141092,0.000009740772,0.001532167,0.9949707,0.00001459806,0.0003264561,0.000002290512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934027,0.0003442804,0.005115791,0.00002549571,0.000003589583,0.00004122983,0.0001494913,0.00005256174,0.0008648256],"genre_scores_gemma":[0.9911854,0.0002480691,0.006878801,0.00003466351,0.000002243516,0.00003512815,0.0003968679,0.00001326387,0.001205612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007806267,"threshold_uncertainty_score":0.001906216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01403362509624423,"score_gpt":0.2780681937258536,"score_spread":0.2640345686296093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}