{"id":"W4306377305","doi":"10.1101/2022.10.12.511923","title":"Cross-sex cecal microbiota transfer alters depressive-like behaviours in mice","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; Memorial University of Newfoundland","funders":"","keywords":"Cecum; Anhedonia; Gut–brain axis; Microbiome; Physiology; Gut microbiome; Depression (economics); Gut flora; Disease; Biology; Internal medicine; Medicine; Psychology; Immunology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006452617,0.0007498823,0.0005240224,0.001641368,0.0004219466,0.0008716825,0.0005740679,0.001502254,0.004613812],"category_scores_gemma":[0.0003538631,0.0006539293,0.0008249132,0.0003671533,0.0008650969,0.0004449202,0.0009277689,0.002417764,0.001441634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000584544,"about_ca_system_score_gemma":0.0003773378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001061007,"about_ca_topic_score_gemma":0.001882095,"domain_scores_codex":[0.999235,0.0001302204,0.00006924904,0.0002354374,0.0001433235,0.0001868191],"domain_scores_gemma":[0.9991536,0.00008024459,0.0002713539,0.0001063118,0.00005970361,0.0003288136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001765154,0.0007327083,0.00110655,0.00007400529,0.00003125338,0.0001871146,0.000129094,0.0001911947,0.991877,0.0005409238,0.000306871,0.003058229],"study_design_scores_gemma":[0.0006180303,0.004748288,0.03470946,0.0001499844,0.0001277061,0.001040904,0.0005707514,0.003509453,0.9422908,0.001003181,0.01115153,0.00007994066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847927,0.001047404,0.005197156,0.0008317211,0.0002273867,0.0001311523,0.00431186,0.0003864267,0.003074225],"genre_scores_gemma":[0.962836,0.001306005,0.009444624,0.001121808,0.00006464087,0.0004817297,0.0028031,0.0004459397,0.02149619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004613812,"threshold_uncertainty_score":0.01543474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01173928695535626,"score_gpt":0.2517548060892364,"score_spread":0.2400155191338801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}