{"id":"W4306377538","doi":"10.3390/curroncol29100618","title":"Therapeutic Advances of Rare ALK Fusions in Non-Small Cell Lung Cancer","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Anaplastic lymphoma kinase; Lung cancer; Cancer research; Fusion gene; Medicine; Crizotinib; Targeted therapy; Population; Fusion protein; Tyrosine kinase; Cancer; Oncology; Biology; Internal medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009485939,0.0002811895,0.001553381,0.0002876277,0.00006081702,0.000002953822,0.0001661201,0.0001550794,0.001567168],"category_scores_gemma":[0.00001351418,0.0002101186,0.00032692,0.0004186062,0.00005674926,0.00002792032,0.00009519498,0.0005353201,0.000007378113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001242691,"about_ca_system_score_gemma":0.002430517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006744404,"about_ca_topic_score_gemma":0.0001598918,"domain_scores_codex":[0.9985039,0.0001449105,0.000566455,0.0003677807,0.000148153,0.0002688259],"domain_scores_gemma":[0.998929,0.0002390282,0.0004110605,0.0002852274,0.0000490893,0.0000865472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001314726,0.0008047727,0.0008907,0.01828538,0.0001710168,0.00003306383,0.000480645,0.000003749338,3.655525e-7,0.00002059332,0.0006208252,0.9786757],"study_design_scores_gemma":[0.001274817,0.0002757107,0.00009899382,0.004975894,0.003656242,0.000016055,0.000151348,0.00001109359,5.809809e-7,0.00000999756,0.9893734,0.0001558317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006715841,0.9885741,0.00001497397,0.00007367273,0.002106656,0.001855112,0.0002016922,0.00001646749,0.007090159],"genre_scores_gemma":[0.0000811347,0.996428,0.00006204194,0.00004607692,0.0001715798,0.002139428,0.0004575918,0.00003902044,0.0005751527],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9887526,"threshold_uncertainty_score":0.9993455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1293771712588524,"score_gpt":0.5041294039134623,"score_spread":0.3747522326546099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}