{"id":"W4306404474","doi":"10.12688/wellcomeopenres.17044.2","title":"Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study","year":2022,"lang":"en","type":"preprint","venue":"Wellcome Open Research","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; National Institute for Health and Care Research; Wellcome Trust","keywords":"Arterial stiffness; Pulse wave velocity; Medicine; Platelet; Immune system; Immunology; Internal medicine; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001383028,0.0003609953,0.0009689878,0.0004140606,0.0009221707,0.0003785942,0.0003157484,0.0001490895,0.0001599503],"category_scores_gemma":[0.0001497718,0.0002790338,0.00002951057,0.0006316122,0.0001818275,0.0001735323,0.001679605,0.001743746,0.000005680944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002180435,"about_ca_system_score_gemma":0.0004056627,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01136217,"about_ca_topic_score_gemma":0.001974969,"domain_scores_codex":[0.9956152,0.001257397,0.0006809529,0.001123914,0.0006403955,0.0006820899],"domain_scores_gemma":[0.9975272,0.0005531033,0.0003559728,0.0008958743,0.0003177299,0.0003500917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008033225,0.001724778,0.970319,0.0006730846,0.0002860144,0.01179089,0.003714319,0.000446204,0.001973521,0.000009868613,0.0000134467,0.001015625],"study_design_scores_gemma":[0.02326337,0.0007311985,0.9541266,0.001577396,0.0002077428,0.001477514,0.009020729,0.0092561,0.00002250811,0.00002503783,0.00001915613,0.000272633],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872188,0.0004933664,0.000007167312,0.0007022833,0.00003649406,0.01108737,0.0001398361,0.00003785754,0.0002768032],"genre_scores_gemma":[0.9966765,0.00004818093,0.0003632561,0.00001340562,0.00002493856,0.00238667,0.0001546078,0.00007919753,0.0002532324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01619241,"threshold_uncertainty_score":0.9999662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05294598668381327,"score_gpt":0.3737389308541085,"score_spread":0.3207929441702952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}