{"id":"W4306404474","doi":"10.12688/wellcomeopenres.17044.2","title":"Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study","year":2022,"lang":"en","type":"preprint","venue":"Wellcome Open Research","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; National Institute for Health and Care Research; Wellcome Trust","keywords":"Arterial stiffness; Pulse wave velocity; Medicine; Platelet; Immune system; Immunology; Internal medicine; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005663913,0.000337167,0.0003127765,0.000528994,0.0008943477,0.0006577891,0.0005239028,0.0005010823,0.001569047],"category_scores_gemma":[0.001801903,0.0006643264,0.0003888907,0.0005731988,0.000557061,0.0003607675,0.0006043519,0.000538884,0.0001799478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003703161,"about_ca_system_score_gemma":0.000289826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01681818,"about_ca_topic_score_gemma":0.0168402,"domain_scores_codex":[0.9994625,0.0001709449,0.00004468286,0.0001562229,0.0000778812,0.00008773211],"domain_scores_gemma":[0.9991391,0.0001677758,0.000347754,0.0001287946,0.00009734515,0.0001192892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001658146,0.00004779352,0.9970379,0.0000257975,0.00007571042,0.0002924566,0.0007969493,0.00001282136,0.0007295531,0.00003006255,0.0001150797,0.0006702149],"study_design_scores_gemma":[0.00001494201,0.000129521,0.9980155,0.00002249209,0.00006183777,0.0007370159,0.0005433033,0.0001686247,0.00007366198,0.00001939866,0.0002089662,0.000004681252],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994463,0.000110041,0.000114051,0.00003441237,0.000003404408,0.000016736,0.0001418417,0.000002220803,0.0001308605],"genre_scores_gemma":[0.999631,0.00005374065,0.00008806548,0.00002178636,0.00000539683,0.00001362042,0.00006511692,9.950207e-7,0.0001204038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01681818,"threshold_uncertainty_score":0.03344053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05294598668381327,"score_gpt":0.3737389308541085,"score_spread":0.3207929441702952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}