{"id":"W4306411462","doi":"10.1016/j.cmi.2022.10.016","title":"Successful immunomodulators for the treatment of COVID-19 have opened the pathway for comparative trials","year":2022,"lang":"en","type":"letter","venue":"Clinical Microbiology and Infection","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Impact; McMaster University","funders":"","keywords":"Medicine; Coronavirus disease 2019 (COVID-19); Guideline; Pandemic; Disease; Clinical trial; Scopus; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus; MEDLINE; Intensive care medicine; Internal medicine; Pathology; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.022647,0.0008499472,0.002821648,0.0008826841,0.002082628,0.004108989,0.002522494,0.02720824,0.009328917],"category_scores_gemma":[0.04009422,0.0003940022,0.002394758,0.0008547951,0.004730384,0.005224253,0.002143707,0.02367271,0.003585728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003147475,"about_ca_system_score_gemma":0.003345585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007127231,"about_ca_topic_score_gemma":0.002148003,"domain_scores_codex":[0.9886826,0.006552921,0.001381462,0.0007151638,0.002000431,0.0006674068],"domain_scores_gemma":[0.9252889,0.06142171,0.002545918,0.001792728,0.004996981,0.003953802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004829007,0.001234184,0.003561947,0.002019921,0.0004233104,0.004743791,0.0003617535,0.0003557536,0.003138685,0.05263002,0.6774317,0.24927],"study_design_scores_gemma":[0.004703233,0.003103856,0.002572279,0.002285548,0.0003032271,0.002732686,0.0005353502,0.0006469237,0.001981108,0.05218783,0.9288256,0.0001223209],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001869282,0.03736027,0.0006894288,0.926018,0.02627418,0.0001074207,0.0001238329,0.00002921931,0.007528407],"genre_scores_gemma":[0.02337385,0.03441567,0.002604445,0.8108549,0.1224734,0.0002943084,0.0001597954,0.0000585375,0.005765091],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02720824,"threshold_uncertainty_score":0.1197702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.274684788365837,"score_gpt":0.5244178126186224,"score_spread":0.2497330242527854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}