{"id":"W4306803090","doi":"10.1111/imcb.12600","title":"Granulocyte–macrophage colony‐stimulating factor–stimulated human macrophages demonstrate enhanced functions contributing to T‐cell activation","year":2022,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"CD80; Granulocyte macrophage colony-stimulating factor; Tumor necrosis factor alpha; CD86; Immunology; Myeloid; Biology; Microglia; Cytokine; Colony-stimulating factor; CD8; T cell; Cytotoxic T cell; Cancer research; Immune system; Cell biology; Inflammation; CD40; Stem cell; Haematopoiesis; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004000807,0.0004001581,0.0005378888,0.0003655617,0.003031241,0.00003107901,0.0002804364,0.0004906678,0.004902067],"category_scores_gemma":[0.0000964364,0.0004187755,0.0001364259,0.0003745192,0.0003024487,0.0001359249,0.0004709823,0.001253512,0.0004928545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001888256,"about_ca_system_score_gemma":0.00006380455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002832491,"about_ca_topic_score_gemma":0.00001083555,"domain_scores_codex":[0.9966545,0.0009277702,0.0006849962,0.0007475688,0.0000441319,0.000941038],"domain_scores_gemma":[0.9986495,0.0004040272,0.0003847644,0.0003617905,0.0001507315,0.00004916643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007793941,0.0002294763,0.002732296,0.00001168376,0.000158271,0.000004554136,0.0004784073,0.0003996796,0.990723,0.0001097943,0.0006153825,0.003758043],"study_design_scores_gemma":[0.00368368,0.00222786,0.01088215,0.00001124113,0.00006636821,0.00006549638,0.001400379,0.00005790081,0.9431983,0.00007805019,0.03782244,0.0005061288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866325,0.001755613,0.002583338,0.0001949796,0.004256873,0.0006438167,0.0000716721,0.0002478932,0.003613323],"genre_scores_gemma":[0.9861193,0.00004503757,0.00003798069,0.0005438831,0.00004939689,0.0001701818,0.001031665,0.00003689458,0.0119656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04752472,"threshold_uncertainty_score":0.9998264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009835854710458348,"score_gpt":0.2450741543438753,"score_spread":0.2352382996334169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}