{"id":"W4306873936","doi":"10.1007/s00018-022-04570-1","title":"Arl13b controls basal cell stemness properties and Hedgehog signaling in the mouse epididymis","year":2022,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique; Université Laval","funders":"","keywords":"Biology; Cell biology; Hedgehog; Cilium; Stem cell; Hedgehog signaling pathway; Keratin 5; Epithelium; Sonic hedgehog; Basal lamina; Cellular differentiation; Keratin 14; Signal transduction; Immunology; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004038902,0.0005804119,0.0004520913,0.001109832,0.0004563686,0.0012609,0.0008536303,0.0008683003,0.003337541],"category_scores_gemma":[0.0002636691,0.0007133585,0.000503427,0.0004008779,0.0009010101,0.0004768858,0.00056127,0.001476392,0.001525836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007966407,"about_ca_system_score_gemma":0.0003690816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001556002,"about_ca_topic_score_gemma":0.003824197,"domain_scores_codex":[0.9991724,0.000106038,0.00008732873,0.0002132149,0.000221099,0.0002000054],"domain_scores_gemma":[0.9993518,0.00006407352,0.000226631,0.00008069951,0.00005307496,0.0002236853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002097417,0.00001879724,0.0003418769,0.00001994714,0.000006876227,0.00007661353,0.00001424239,0.00004609119,0.9983566,0.0002617976,0.00006006599,0.0005872445],"study_design_scores_gemma":[0.00005008457,0.00007953206,0.01422151,0.0000136483,0.00003285109,0.0002553194,0.0001006945,0.0009027428,0.9812073,0.0001223084,0.003002598,0.00001142247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882157,0.002410509,0.003783078,0.000294633,0.00008783973,0.00002030662,0.001912605,0.0003127642,0.0029625],"genre_scores_gemma":[0.9819441,0.0006591362,0.002042428,0.0001940975,0.00001841404,0.00004995721,0.001520617,0.0003216294,0.01324963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003337541,"threshold_uncertainty_score":0.01116514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01723894248462424,"score_gpt":0.2121915880847195,"score_spread":0.1949526456000953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}