{"id":"W4306913672","doi":"10.1182/bloodadvances.2022007698","title":"The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; American Society of Hematology","keywords":"Medicine; Psychological intervention; Newborn screening; Population; Pediatrics; Clinical trial; Cohort; Disease; Malaria; Intervention (counseling); Family medicine; Environmental health; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02681393,0.001764305,0.001542683,0.002909132,0.003318907,0.002386204,0.003193374,0.002310598,0.01776023],"category_scores_gemma":[0.02882913,0.001298761,0.001503128,0.004333586,0.001877913,0.00177918,0.003110878,0.002879442,0.003975635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003671208,"about_ca_system_score_gemma":0.0233329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01044522,"about_ca_topic_score_gemma":0.01455798,"domain_scores_codex":[0.9792835,0.01470008,0.001704617,0.001720566,0.001535799,0.001055348],"domain_scores_gemma":[0.9865111,0.003388213,0.001631913,0.001621978,0.004458738,0.002388029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.05189415,0.0183082,0.2596064,0.02283353,0.002146097,0.004109959,0.01531843,0.003046412,0.003317683,0.08510967,0.1671713,0.3671382],"study_design_scores_gemma":[0.04532603,0.03014452,0.1531842,0.01998902,0.003528037,0.002852425,0.01548594,0.005884378,0.00389605,0.03374064,0.6854048,0.0005640273],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.04186032,0.007638839,0.02041705,0.004972647,0.001906182,0.8897949,0.0159294,0.0001322837,0.01734834],"genre_scores_gemma":[0.03614362,0.002272463,0.03355243,0.003754199,0.0004615375,0.9176264,0.003289873,0.00003529111,0.002864102],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02681393,"threshold_uncertainty_score":0.1418073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04934728364081688,"score_gpt":0.3105040835364912,"score_spread":0.2611567998956743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}