{"id":"W4306965209","doi":"10.1101/2022.10.19.512974","title":"Glycogen degrading activities of catalytic domains of α-amylase and α-amylase-pullulanase enzymes conserved in <i>Gardnerella</i> spp. from the vaginal microbiome","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of Saskatchewan","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Maltotriose; Pullulanase; Maltose; Amylase; Glycogen debranching enzyme; Biochemistry; Biology; Glycogen; Microbiology; Enzyme; Glycogen synthase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526307,0.0004105152,0.000275255,0.0004763669,0.0001308429,0.0005679408,0.0001678111,0.0002476497,0.000614301],"category_scores_gemma":[0.0003567121,0.0001362272,0.0005631598,0.0004827085,0.0001435296,0.0002401663,0.0002972358,0.0002417668,0.0003325221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001601843,"about_ca_system_score_gemma":0.0001856537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001893909,"about_ca_topic_score_gemma":0.0009840149,"domain_scores_codex":[0.9998381,0.00001579917,0.00002628464,0.00004446615,0.00003784476,0.00003737615],"domain_scores_gemma":[0.9998335,0.00002756678,0.00004486207,0.00001262028,0.00004207467,0.00003941016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001130226,0.00001866428,0.00465397,0.00006991874,0.00001557645,0.00008733287,0.00005668438,0.00005480632,0.9931283,0.00002237646,0.00003069551,0.001748555],"study_design_scores_gemma":[0.00001562425,0.0003010026,0.1870972,0.00005068982,0.000122783,0.002074501,0.0005446814,0.002403417,0.8033436,0.0001095747,0.003913823,0.00002308949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958318,0.00101517,0.001258288,0.00004366652,0.00001420858,0.00001559218,0.001262788,0.00002824546,0.0005301423],"genre_scores_gemma":[0.9908054,0.0005367866,0.003223165,0.00004475532,0.000007364679,0.00002053581,0.004563587,0.00001757405,0.0007808676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001893909,"threshold_uncertainty_score":0.003765821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00946471517849864,"score_gpt":0.2056061827026637,"score_spread":0.1961414675241651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}