{"id":"W4306965209","doi":"10.1101/2022.10.19.512974","title":"Glycogen degrading activities of catalytic domains of α-amylase and α-amylase-pullulanase enzymes conserved in <i>Gardnerella</i> spp. from the vaginal microbiome","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of Saskatchewan","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; University of Saskatchewan","keywords":"Maltotriose; Pullulanase; Maltose; Amylase; Glycogen debranching enzyme; Biochemistry; Biology; Glycogen; Microbiology; Enzyme; Glycogen synthase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003925963,0.0003359402,0.0004262296,0.0001368384,0.00009393559,0.00004455921,0.0003673894,0.0002505042,0.00003225457],"category_scores_gemma":[0.0001230293,0.0003286772,0.00009857064,0.0002307991,0.0002628994,0.00001080038,0.0005025262,0.0003348631,0.000001180813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005930408,"about_ca_system_score_gemma":0.0003430199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000340871,"about_ca_topic_score_gemma":0.00002799595,"domain_scores_codex":[0.9981666,0.0002291896,0.0004951865,0.0006741197,0.0001854258,0.0002494333],"domain_scores_gemma":[0.9984179,0.00005284653,0.0004980224,0.0008325753,0.0001173695,0.00008131613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001711116,0.0001112072,0.01617461,0.000178277,0.0001532958,0.00001004925,0.00003327668,0.0000338869,0.9827534,0.00004895297,0.0003306897,0.000001223367],"study_design_scores_gemma":[0.0006491607,0.00006919361,0.02351853,0.0001051073,0.00009468078,1.138775e-7,0.00005531721,0.00002355527,0.9718208,0.000002306631,0.003337438,0.0003237927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933467,0.00439772,0.00009300983,0.0001653607,0.0004011978,0.0003779203,0.001190156,0.00002228453,0.000005669106],"genre_scores_gemma":[0.9984239,0.0006928465,0.0003758894,0.0001287697,0.0002147902,0.00006139625,0.00003195478,0.00005847475,0.0000120099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01093262,"threshold_uncertainty_score":0.9999166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00946471517849864,"score_gpt":0.2056061827026637,"score_spread":0.1961414675241651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}