{"id":"W4307030592","doi":"10.32920/21290955","title":"Biodegradable polymeric nanoparticles containing gold nanoparticles and Paclitaxel for cancer imaging and drug delivery using photoacoustic methods","year":2022,"lang":"en","type":"preprint","venue":"","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Chongqing Medical University","keywords":"PLGA; Paclitaxel; Photoacoustic imaging in biomedicine; Drug delivery; Nanoparticle; Materials science; Colloidal gold; Nanotechnology; Nanomedicine; Cancer cell; Vaporization; Biomedical engineering; Biodegradable polymer; Polymer; Cancer; Chemistry; Medicine; Organic chemistry; Composite material; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001261612,0.0002958375,0.00009683068,0.000179298,0.00008204551,0.0002289983,0.0001409176,0.0003338273,0.001042679],"category_scores_gemma":[0.0001289737,0.0001324301,0.000116947,0.0001000478,0.0002000112,0.0003427401,0.000192334,0.0002369547,0.0004614215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000297884,"about_ca_system_score_gemma":0.0001647354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004778258,"about_ca_topic_score_gemma":0.000568337,"domain_scores_codex":[0.9999123,0.00001007527,0.000004637877,0.00002153033,0.00003849882,0.00001302323],"domain_scores_gemma":[0.9999672,0.0000086359,0.00001028659,0.000003814615,0.000005582301,0.000004475156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001442823,0.00001058436,0.00002238088,0.00002696863,0.000002243485,0.00003769188,0.00001106075,0.0003176965,0.9942694,0.0004272147,0.00007162258,0.004788789],"study_design_scores_gemma":[0.000006517428,0.00005331643,0.0001203564,0.000002512012,0.000004531109,0.00007790248,0.000004630963,0.002287347,0.9934714,0.00009330217,0.003874738,0.000003424448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8132032,0.01093606,0.1541542,0.0009590673,0.000320863,0.0002136324,0.0001508453,0.001178652,0.01888349],"genre_scores_gemma":[0.9162451,0.002574858,0.05730536,0.0002180441,0.00003701226,0.00007186287,0.0001226008,0.0001028188,0.02332236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042679,"threshold_uncertainty_score":0.003488183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02452923426531078,"score_gpt":0.2966736093562284,"score_spread":0.2721443750909177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}