{"id":"W4307039470","doi":"10.1016/j.jtbi.2022.111312","title":"Multi-scale model of lumen formation via inverse membrane blebbing mechanism during sprouting angiogenesis process","year":2022,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Mathematical Biology Tumor Growth","field":"Mathematics","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Angiogenesis; Lumen (anatomy); Mechanism (biology); Cell biology; Biology; Cancer research; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002059779,0.0002002107,0.0006904957,0.0002373867,0.0001778343,0.000007303501,0.0005082009,0.0001426469,0.0003865107],"category_scores_gemma":[0.0009168183,0.0001548556,0.0002791006,0.0002047761,0.0003287406,0.0001170064,0.0003022698,0.0004140274,0.000003498339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000110813,"about_ca_system_score_gemma":0.00005476754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.141948e-7,"about_ca_topic_score_gemma":7.830755e-7,"domain_scores_codex":[0.9975472,0.0004241318,0.001182542,0.0001901856,0.0002806341,0.0003752894],"domain_scores_gemma":[0.9979413,0.0005077182,0.0009909173,0.0002288852,0.0002065527,0.0001246479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002595765,0.000337619,0.0001789919,0.0003872924,0.0001055437,0.00001225472,0.001453486,0.0003408381,0.5901345,0.4066916,0.000008696525,0.00008954397],"study_design_scores_gemma":[0.0008458768,0.0002767098,0.000005604237,0.0000421155,0.0001262814,0.0003561749,0.0006402828,0.1285034,0.2183965,0.6506649,8.36513e-7,0.0001414312],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8634571,0.00002098373,0.1356432,0.0002591805,0.0001071508,0.0002140721,0.00002457472,0.00002560184,0.0002480453],"genre_scores_gemma":[0.9317674,0.000006031328,0.06804921,0.00006654431,0.00004756996,0.00001626778,0.000003420747,0.00002503099,0.00001853953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.371738,"threshold_uncertainty_score":0.6314826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02891937638190739,"score_gpt":0.2897664225184018,"score_spread":0.2608470461364944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}