{"id":"W4307042006","doi":"10.1016/j.matbio.2022.10.003","title":"Degradomics technologies in matrisome exploration","year":2022,"lang":"en","type":"review","venue":"Matrix Biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Novo Nordisk Fonden; Novo Nordisk","keywords":"Computational biology; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001239866,0.0003010599,0.0009187692,0.0002687637,0.00008157465,0.00001352722,0.000626212,0.0006765067,0.0003776218],"category_scores_gemma":[0.00006811486,0.0002745589,0.0002051719,0.0004115203,0.0000794642,0.00004609024,0.0003890451,0.0008219735,0.00004608721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037424,"about_ca_system_score_gemma":0.00008325573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001396076,"about_ca_topic_score_gemma":0.000004634937,"domain_scores_codex":[0.9985773,0.0000358196,0.0005878182,0.0004759333,0.00004713541,0.0002760131],"domain_scores_gemma":[0.998833,0.0001573664,0.0003800402,0.0006032695,0.000009218516,0.00001708668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002644703,0.00003046634,0.000005827238,0.001788641,0.00001332412,0.000003903881,0.000006047959,0.000001417388,0.0000467266,0.01426964,0.0001130745,0.9837183],"study_design_scores_gemma":[0.00006967031,0.00001251921,5.713515e-9,0.0002438266,0.00004083217,0.00002114887,0.00006810624,0.0000063991,0.0001007163,0.02578011,0.9733932,0.0002634496],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000005380019,0.9949697,0.002501026,0.0000767162,0.00004329499,0.000451232,0.0001979183,0.0006520039,0.00110268],"genre_scores_gemma":[0.000005716068,0.9831837,0.01185682,0.000004197342,0.00004387165,0.003490798,0.0009700285,0.00005117049,0.0003936325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9834548,"threshold_uncertainty_score":0.9999707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06878021764178267,"score_gpt":0.3823468319278974,"score_spread":0.3135666142861148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}