{"id":"W4307054616","doi":"10.1016/j.jtct.2022.10.011","title":"Profiling the Fungal Microbiome after Fecal Microbiota Transplantation for Graft-versus-Host Disease: Insights from a Phase 1 Interventional Study","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; DKMS Foundation; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Seres Therapeutics; ZonMw; National Heart, Lung, and Blood Institute; Landsteiner Foundation for Blood Transfusion Research; Ludwig Center at Harvard; Merck; Deutsche Forschungsgemeinschaft; Academisch Medisch Centrum; European Hematology Association; Memorial Sloan-Kettering Cancer Center; National Institute on Aging; Parker Institute for Cancer Immunotherapy; Lymphoma Foundation; ADC Foundation","keywords":"Mycobiota; Microbiome; Biology; Transplantation; Graft-versus-host disease; Hematopoietic stem cell transplantation; Context (archaeology); Gut flora; Feces; Immunology; Microbiology; Medicine; Internal medicine; Ecology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008208776,0.0004966998,0.000737196,0.0002301141,0.000297027,0.0008897107,0.0001900045,0.0006035492,0.001164688],"category_scores_gemma":[0.000397272,0.0001564501,0.0004280536,0.0002622051,0.0004753463,0.0004007881,0.0002632323,0.0009830568,0.000219958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000256545,"about_ca_system_score_gemma":0.0005785823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001738741,"about_ca_topic_score_gemma":0.0004538101,"domain_scores_codex":[0.9997066,0.00008936611,0.0000092625,0.00004812029,0.00006136797,0.00008528375],"domain_scores_gemma":[0.9997599,0.00003336299,0.00007018093,0.00003217119,0.00002855498,0.00007584967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.024784,0.007219242,0.01137598,0.0002420823,0.0002012217,0.0001276453,0.0001520352,0.0004291971,0.9037972,0.0002562205,0.0007382531,0.05067691],"study_design_scores_gemma":[0.004590573,0.2355572,0.244001,0.0002087707,0.001314381,0.001876187,0.001026148,0.003670333,0.4928325,0.001105204,0.01370636,0.0001112787],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955786,0.001642594,0.00158151,0.0001476085,0.00006009683,0.000218991,0.0002608506,0.00002387607,0.0004859935],"genre_scores_gemma":[0.9927872,0.002252237,0.002428636,0.0004098965,0.00006453243,0.0002936732,0.0008319348,0.00002412093,0.0009078257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001164688,"threshold_uncertainty_score":0.004341245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01742214589055315,"score_gpt":0.2839128137242455,"score_spread":0.2664906678336924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}