{"id":"W4307054616","doi":"10.1016/j.jtct.2022.10.011","title":"Profiling the Fungal Microbiome after Fecal Microbiota Transplantation for Graft-versus-Host Disease: Insights from a Phase 1 Interventional Study","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; DKMS Foundation; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Seres Therapeutics; ZonMw; National Heart, Lung, and Blood Institute; Landsteiner Foundation for Blood Transfusion Research; Ludwig Center at Harvard; Merck; Deutsche Forschungsgemeinschaft; Academisch Medisch Centrum; European Hematology Association; Memorial Sloan-Kettering Cancer Center; National Institute on Aging; Parker Institute for Cancer Immunotherapy; Lymphoma Foundation; ADC Foundation","keywords":"Mycobiota; Microbiome; Biology; Transplantation; Graft-versus-host disease; Hematopoietic stem cell transplantation; Context (archaeology); Gut flora; Feces; Immunology; Microbiology; Medicine; Internal medicine; Ecology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001440003,0.0001865963,0.0001297855,0.00005436802,0.0004343855,0.00004586699,0.0001430297,0.00005078051,0.0001015544],"category_scores_gemma":[0.000001063667,0.0001548113,0.0001367369,0.00007696568,0.00005677188,0.000009802821,0.00001425042,0.0001198052,0.000002010912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001678666,"about_ca_system_score_gemma":0.0000634025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002630892,"about_ca_topic_score_gemma":0.00008161652,"domain_scores_codex":[0.9988249,0.0002102319,0.0002633109,0.0004025032,0.0001129535,0.0001860921],"domain_scores_gemma":[0.9996139,0.00002965504,0.00007584644,0.000169057,0.00003728735,0.00007420219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01501139,0.0009159687,0.0008988986,0.00006764213,0.0001496006,0.00002290254,0.001632617,0.00001006166,0.9807784,0.00004893339,0.00004849752,0.0004150989],"study_design_scores_gemma":[0.09060602,0.01169115,0.07493146,0.00009520291,0.001057807,0.0001054161,0.00481093,0.0003198246,0.7749831,0.0001947546,0.0395247,0.001679604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881161,0.003645951,0.004301304,0.0001722087,0.0003021282,0.001210668,0.002229599,0.00001508436,0.000006893593],"genre_scores_gemma":[0.9914226,0.000635082,0.0001428333,0.0002803419,0.0001222439,0.0003649225,0.00690288,0.0000270777,0.0001020048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2057953,"threshold_uncertainty_score":0.6313023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01742214589055315,"score_gpt":0.2839128137242455,"score_spread":0.2664906678336924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}