{"id":"W4307137789","doi":"10.1089/ipm.09.05.03","title":"Is Clinical Next-Generation Sequencing on the Cusp of a Revolution?","year":2022,"lang":"en","type":"article","venue":"Inside Precision Medicine","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CARE Canada","funders":"","keywords":"Cusp (singularity); Precision medicine; Clinical Oncology; Library science; Medicine; Family medicine; Medical education; Internal medicine; Computer science; Pathology; Mathematics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1023853,0.001620837,0.005134608,0.002207744,0.002955249,0.01087171,0.004846233,0.01606626,0.01784631],"category_scores_gemma":[0.1316794,0.0009821834,0.00219508,0.002053644,0.01837737,0.0321434,0.007300151,0.02460728,0.004750445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005054025,"about_ca_system_score_gemma":0.01506929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003463703,"about_ca_topic_score_gemma":0.003947756,"domain_scores_codex":[0.9736021,0.01216019,0.001668401,0.002849071,0.007500259,0.00221994],"domain_scores_gemma":[0.7947598,0.1561528,0.004741861,0.008661117,0.02016772,0.01551673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00148036,0.0003767132,0.003740202,0.003124026,0.0003986095,0.0005755072,0.0008005644,0.002555321,0.002689685,0.2739861,0.3454902,0.3647827],"study_design_scores_gemma":[0.0002232995,0.0004444153,0.002200545,0.004281139,0.0002160754,0.0006186125,0.001170192,0.001822956,0.0008010752,0.5086201,0.4793906,0.0002110008],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001795001,0.1741954,0.01346847,0.7887152,0.01535721,0.0000377733,0.0003458335,0.0003402572,0.005744839],"genre_scores_gemma":[0.07375167,0.2759763,0.03206955,0.5310715,0.08126544,0.0003048658,0.000988581,0.0004090913,0.004163072],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1023853,"threshold_uncertainty_score":0.5414718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1460222548571488,"score_gpt":0.3496886302170572,"score_spread":0.2036663753599083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}