{"id":"W4307154696","doi":"10.1016/j.clml.2022.10.005","title":"Real-world Outcomes With Cumulative Bortezomib Dose and Efficacy in the Treatment of Transplant-ineligible Multiple Myeloma With Cyclophosphamide, Bortezomib, and Dexamethasone","year":2022,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Baker Hughes (Canada); Alberta Cancer Foundation","funders":"","keywords":"Bortezomib; Discontinuation; Medicine; Cumulative dose; Multiple myeloma; Dexamethasone; Internal medicine; Cyclophosphamide; Cumulative incidence; Gastroenterology; Oncology; Surgery; Cohort; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001964526,0.0002526693,0.0005420971,0.0003187408,0.0002625117,0.001295423,0.0005082663,0.0007818458,0.001902302],"category_scores_gemma":[0.006827711,0.0001709991,0.001124862,0.0007422574,0.0005355138,0.001127445,0.0006455616,0.001152176,0.0002306065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001134529,"about_ca_system_score_gemma":0.0004215924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002862869,"about_ca_topic_score_gemma":0.002899822,"domain_scores_codex":[0.9988311,0.0005221301,0.0001303858,0.0002106794,0.0001081268,0.0001976326],"domain_scores_gemma":[0.9931026,0.002029562,0.00326359,0.0003015828,0.0002460879,0.001056565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03526058,0.0009691778,0.9406984,0.0001191204,0.001519143,0.0002630591,0.0001929446,0.006206111,0.0004681947,0.0003434754,0.001598819,0.01236085],"study_design_scores_gemma":[0.0008938581,0.004683198,0.988098,0.0000368242,0.0004601122,0.0003922808,0.0002701331,0.003697051,0.0002049394,0.0003277851,0.0008866687,0.00004909169],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974313,0.0007085532,0.00007090608,0.0001863001,0.0000114923,0.00001101435,0.001102791,0.000005351126,0.0004721875],"genre_scores_gemma":[0.9990197,0.00008445666,0.00002982744,0.00004067305,0.000009642195,0.000007711447,0.0007622483,0.000001531756,0.00004421756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002862869,"threshold_uncertainty_score":0.01038951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04323960663855163,"score_gpt":0.3505000595739032,"score_spread":0.3072604529353515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}