{"id":"W4307178822","doi":"10.15252/embr.202255044","title":"SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination","year":2022,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Sinai Health System; Occupational Cancer Research Centre; University of Toronto","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Terry Fox Research Institute","keywords":"Ubiquitin ligase; Ubiquitin; Mitosis; F-box protein; Mutation; Cell cycle; Biology; Cell biology; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001597851,0.0003561019,0.0002540476,0.0003480792,0.000436797,0.001029619,0.0004195271,0.0004488569,0.00245496],"category_scores_gemma":[0.0001906669,0.0001750427,0.000234449,0.0002409117,0.0004067825,0.0005080962,0.0004420562,0.0005579795,0.0009628398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001084523,"about_ca_system_score_gemma":0.0004466473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001954511,"about_ca_topic_score_gemma":0.003771754,"domain_scores_codex":[0.9998364,0.00001469286,0.00001132457,0.00003957279,0.00003042139,0.00006757867],"domain_scores_gemma":[0.9998486,0.00001330238,0.0000401199,0.00001286735,0.00002419795,0.00006084674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004476373,0.00002651977,0.0007307684,0.00005041417,0.000009109594,0.0001093853,0.00001871757,0.00009551804,0.9951876,0.0005754899,0.0002470867,0.00250173],"study_design_scores_gemma":[0.00004195693,0.00006635984,0.01392735,0.000009424509,0.00001366313,0.0001404854,0.00007924491,0.002014151,0.9799479,0.0001881603,0.003562279,0.000009090314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896263,0.003735921,0.002117158,0.0003701092,0.00007885518,0.00001915978,0.0005834954,0.0002091661,0.003259929],"genre_scores_gemma":[0.9956161,0.0004472662,0.0005168841,0.00005711902,0.000008144666,0.00001213585,0.0004365721,0.00003576743,0.002870116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00245496,"threshold_uncertainty_score":0.008212686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038870465459933,"score_gpt":0.2638863362335928,"score_spread":0.2534976315789935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}