{"id":"W4307233431","doi":"10.1042/bst20220621","title":"Cancer cells hijack RNA processing to rewrite the message","year":2022,"lang":"en","type":"article","venue":"Biochemical Society Transactions","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute","keywords":"Biology; RNA; RNA splicing; Messenger RNA; Polyadenylation; Translation (biology); Computational biology; Cell biology; Post-transcriptional modification; Intron; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001747757,0.0001107847,0.00008405098,0.0000100766,0.0007297599,0.00003562222,0.0002912503,0.00006776855,0.0002625774],"category_scores_gemma":[0.000006607926,0.00009101124,0.0002147854,0.000259034,0.00007820458,0.000003360404,0.00005557097,0.0002960141,0.00000506207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006763048,"about_ca_system_score_gemma":0.0001198523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009182937,"about_ca_topic_score_gemma":0.00001082182,"domain_scores_codex":[0.9989495,0.00004092767,0.0001292394,0.000303903,0.0002548072,0.0003216032],"domain_scores_gemma":[0.9995496,0.00001206052,0.00002675999,0.000227428,0.00004879746,0.0001353673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002895095,0.00005141294,0.00001028741,0.00001260139,0.0000402433,3.849736e-7,0.0001703103,0.0005641699,0.9661762,0.000001634355,0.02927161,0.003672153],"study_design_scores_gemma":[0.000222256,0.00006674404,0.00004800011,0.000006155569,0.00002042223,0.000003941769,0.0007580623,0.0006598238,0.8850207,0.000005972244,0.1130363,0.0001516282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622236,0.001800953,0.02800942,0.006968007,0.0001381536,0.0003603349,0.0001461539,0.0000339137,0.0003194034],"genre_scores_gemma":[0.9917893,0.0002630807,0.0007783645,0.001853005,0.0001565135,0.0003275493,0.00002736503,0.00002293689,0.004781836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08376467,"threshold_uncertainty_score":0.5612797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238495348105354,"score_gpt":0.2780489271861347,"score_spread":0.2656639737050811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}