{"id":"W4307280491","doi":"10.3389/fpsyt.2022.989050","title":"A comparative magnetic resonance spectroscopy study of GABA+ and glutamate referenced to creatine and phosphocreatine in the left dorsolateral prefrontal cortex of perimenopausal women and women of reproductive age","year":2022,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Alexandra Hospital; NOSM University; Women and Children’s Health Research Institute; University of Alberta","funders":"Janssen Canada","keywords":"Phosphocreatine; Dorsolateral prefrontal cortex; Creatine; Glutamate receptor; Prefrontal cortex; Medicine; Magnetic resonance imaging; Psychology; Internal medicine; Nuclear magnetic resonance; Neuroscience; Physics; Cognition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001521361,0.000143363,0.0001530954,0.0003603309,0.0001797568,0.0001742459,0.0001123975,0.0001838962,0.001079689],"category_scores_gemma":[0.0006846589,0.0001423185,0.00008146757,0.0001652651,0.0001500197,0.000117074,0.0001462729,0.0001122368,0.0001335243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001464369,"about_ca_system_score_gemma":0.0001141629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002038645,"about_ca_topic_score_gemma":0.003031054,"domain_scores_codex":[0.9999559,0.000009267692,0.000003214371,0.00001277955,0.00000726062,0.00001154646],"domain_scores_gemma":[0.9998507,0.00003490052,0.00004282534,0.00000970229,0.00001733355,0.00004452472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006728109,0.0003379671,0.8979501,0.00009800807,0.0002232323,0.002235042,0.002076466,0.00006219277,0.07120652,0.00007609066,0.0001458671,0.01886036],"study_design_scores_gemma":[0.00002753526,0.000388537,0.9982057,0.000001695246,0.00001632856,0.0007197901,0.0002388861,0.00003735728,0.000262068,0.00001551404,0.00008504638,0.00000144787],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997097,0.0001036802,0.00002583325,0.000008167748,0.000001243621,0.000002727129,0.00002732397,6.578877e-7,0.000120758],"genre_scores_gemma":[0.9996601,0.00006496089,0.00007007915,0.00002313311,0.000003376994,0.000004898175,0.00004959395,8.528173e-7,0.0001231321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038645,"threshold_uncertainty_score":0.004053593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01344698745810828,"score_gpt":0.2959789890405654,"score_spread":0.2825320015824571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}