{"id":"W4307338125","doi":"10.1161/jaha.122.026619","title":"No Mediation Effect of Telomere Length or Mitochondrial DNA Copy Number on the Association Between Adverse Childhood Experiences (ACEs) and Central Arterial Stiffness","year":2022,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Birth, Development, and Health","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Canadian Institutes of Health Research; Brock University","keywords":"Medicine; Telomere; Adverse Childhood Experiences; Mediation; Mitochondrial DNA; Arterial stiffness; Adverse effect; Oxidative stress; Genetics; Internal medicine; DNA; Gene; Psychiatry; Blood pressure; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001427562,0.0005618921,0.000333445,0.0002662856,0.0002657408,0.0006069636,0.0005218121,0.0002944871,0.006220078],"category_scores_gemma":[0.009085759,0.0002797591,0.0005430366,0.0002473371,0.0004733595,0.0004740208,0.0007025239,0.000417274,0.0002410279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001940408,"about_ca_system_score_gemma":0.000585201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004369809,"about_ca_topic_score_gemma":0.00512768,"domain_scores_codex":[0.9993008,0.0003061338,0.00003576462,0.000168765,0.00007620468,0.0001122878],"domain_scores_gemma":[0.9935365,0.003987231,0.001322155,0.0005200334,0.0002279943,0.0004060592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001545993,0.00009833415,0.9824409,0.0001319327,0.0005048572,0.0002863269,0.0004215944,0.0001751697,0.003315793,0.0003847188,0.0002249423,0.01046939],"study_design_scores_gemma":[0.00003097885,0.0002938298,0.9964722,0.00004219018,0.0003086637,0.000290419,0.0002523348,0.0008115915,0.0006010605,0.0004261838,0.000462301,0.000008304341],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957867,0.001240378,0.0009405364,0.00023139,0.00003133566,0.00001890809,0.0004854139,0.00001676324,0.00124859],"genre_scores_gemma":[0.9988455,0.000225982,0.0002823719,0.00003564061,0.00001352199,0.00001318709,0.0001209824,0.000003638335,0.0004592226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006220078,"threshold_uncertainty_score":0.02080822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008780847082131374,"score_gpt":0.2758765184996521,"score_spread":0.2670956714175207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}