{"id":"W4307349457","doi":"10.1101/2022.10.20.512941","title":"The priming effect of rewarding brain stimulation in rats depends on both the cost and strength of reward but survives blockade of D2-like dopamine receptors","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Concordia University","keywords":"Medial forebrain bundle; Brain stimulation reward; Neuroscience; Eticlopride; Psychology; Electrical brain stimulation; Stimulation; Dopamine; Dopaminergic; Priming (agriculture); Reward system; Brain stimulation; Nucleus accumbens; SCH-23390; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000318038,0.001141698,0.000650314,0.0004556869,0.0001654032,0.0003073074,0.0004287703,0.0004744159,0.002002904],"category_scores_gemma":[0.0003272453,0.0004645477,0.0004916588,0.0001691548,0.0008929992,0.0004402419,0.0003770823,0.001782244,0.0002480548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004050242,"about_ca_system_score_gemma":0.0005117942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005523997,"about_ca_topic_score_gemma":0.001065793,"domain_scores_codex":[0.9996893,0.00004071612,0.00003015596,0.00008343894,0.00005078421,0.0001055641],"domain_scores_gemma":[0.9993692,0.000132164,0.0001916366,0.00009102092,0.00002505036,0.0001909605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008368144,0.00009203949,0.00010396,0.00002215936,0.000006022236,0.00003781846,0.00001065687,0.00004246236,0.9978739,0.00009487984,0.00001787435,0.0008612758],"study_design_scores_gemma":[0.0001223784,0.003736333,0.004352119,0.000007931962,0.00002562801,0.0001423895,0.00001726967,0.0009060926,0.9902231,0.0001442477,0.0003094979,0.00001303762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975365,0.0001786997,0.001475516,0.00007589884,0.00003336755,0.00003560294,0.0001495076,0.0001288034,0.0003859412],"genre_scores_gemma":[0.9919552,0.0003076674,0.005450061,0.00008159187,0.00003339731,0.0001811017,0.0002314252,0.00007020128,0.001689458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002002904,"threshold_uncertainty_score":0.006700337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02154496470734543,"score_gpt":0.2642853122175083,"score_spread":0.2427403475101629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}